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Publications 2017 (IKP + RBK)

  • Aabakken L, Karlsen TH, Albert J, Arvanitakis M, Chazouilleres O, Dumonceau J-M, Färkkilä M, Fickert P, Hirschfield GM, Laghi A, Marzioni M, Fernandez M, Pereira SP, Pohl J, Poley J-W, Ponsioen CY, Schramm C, Swahn F, Tringali A, Hassan C. Role of endoscopy in primary sclerosing cholangitis, European Society of Gastrointestinal Endoscopy (ESGE) and European Association for the Study of the Liver (EASL) Clinical Guideline. Endoscopy;49:588–608 2017.
  • Agewall S, Beltrame JF, Reynolds HR, Niessner A, Rosano G, Caforio ALP, Caterina R de, Zimarino M, Roffi M, Kjeldsen K, Atar D, Kaski JC, Sechtem U, Tornvall P. ESC working group position paper on myocardial infarction with non-obstructive coronary arteries. Eur Heart J;38:143–53 2017.
  • Ahad S, Wachter K, Rustenbach C, Stan A, Hill S, Schäufele T, Ursulescu A, Franke UFW, Baumbach H. Concomitant therapy, Off-pump coronary revascularization and transcatheter aortic valve implantation. Interact Cardiovasc Thorac Surg;25:12–7 2017.
  • Allgäuer S, Pieper F, Mahrholdt H. Schwere akzidentelle Hypothermie, Behandlung mithilfe eines intravaskulären Katheters zum Temperaturmanagement [Severe accidental hypothermia : Treatment using an intravascular temperature management catheter]. Med Klin Intensivmed Notfmed 2017.
  • Authors (Strassburg CP, Beckebaum S, Geier A, Gotthardt D, Klein R, Melter M, Schott E, Spengler U, Tacke F, Trauner M, Weiler-Normann C, Weismüller TJ, Tannapfel A, Tischendorf JJ, Schramm C), Collaborators: (Albert j, Allescher HD, Antoni C, Berg C, Bufler P, Dannel F, Dietrich C, Engelmann G, Feist E, Fickert P, Fischer L, Flechtenmacher C, Friedrich-Rust M, Giek A, Görtz RS, Herzer K, Hofer H, Hohenester S, Höhn M, Hüppe D, In der Smitten S, Jahnel J, Keitel-Anselmino V, Kirchner G, Kremer A, Lauenstein A, Lenzen H, Mayerle J, Müller T, Müllhaupt B, Nashan B, Rust C, Schattenberg JM, Schmidt H, Schreyer A, Sebode M, Siegmund B, Terjung B, Teufel A, van Thiel I, Wirth S, Witte T), Externe Begutachtung durch:Fachgesellschaften: Deutsche Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS) (federführend), Deutsche Gesellschaft für Innere Medizin (DGIM), Deutsche M. Crohn/Colitis ulcerosa Vereinigung (DCCV), Deutsche Leberhilfe e.V., Deutsche Gesellschaft für Ultraschall in der Medizin (DEGUM), Deutsche Gesellschaft für Endoskopie und Bildgebende Verfahren (DGE-BV), Deutsche Gesellschaft für Kinder- und Jugendmedizin (DGKJ), Gesellschaft für Pädiatrische Gastroenterologie (GPGE), Deutsche Gesellschaft für Rheumatologie (DGRh), Deutsche Röntgengesellschaft (DRG), Deutsche Transplantationsgesellschaft (DTG), Deutsche Gesellschaft für Pathologie (DGP) und Bundesverband Deutscher Pathologen (BDP), Österreichische Gesellschaft für Gastroenterologie (ÖGG), Schweizer Gastroenterologische Gesellschaft (SGG). S2k Leitlinie Autoimmune Lebererkrankungen [Practice guideline autoimmune liver diseases - AWMF-Reg. No. 021-27]. Z Gastroenterol;55:1135–226 2017.
  • Aziz A, Hansen HS, Sechtem U, Prescott E, Ong P. Sex-Related Differences in Vasomotor Function in Patients With Angina and Unobstructed Coronary Arteries. J Am Coll Cardiol;70:2349–58 2017.
  • Aziz O, Klenk J, Schwickert L, Chiari L, Becker C, Park EJ, Mori G, Robinovitch SN. Validation of accuracy of SVM-based fall detection system using real-world fall and non-fall datasets. PLoS ONE;12:e0180318 2017.
  • Baumbach H, Ahad S, Rustenbach C, Hill S, Schäufele T, Wachter K, Franke UFW. Conventional versus Transapical Aortic Valve Replacement, Is It Time for Shift in Indications? Thorac Cardiovasc Surg;65:212–7 2017.
  • Barrdahl M, Rudolph A, Hopper JL, Southey MC, Broeks A, Fasching PA, Beckmann MW, Gago-Dominguez M, Castelao JE, Guénel P, Truong T, Bojesen SE, Gapstur SM, Gaudet MM, Brenner H, Arndt V, Brauch H, Hamann U, Mannermaa A, Lambrechts D, Jongen L, Flesch-Janys D, Thoene K, Couch FJ, Giles GG, Simard J, Goldberg MS, Figueroa J, Michailidou K, Bolla MK, Dennis J, Wang Q, Eilber U, Behrens S, Czene K, Hall P, Cox A, Cross S, Swerdlow A, Schoemaker MJ, Dunning AM, Kaaks R, Pharoah PDP, Schmidt M, Garcia-Closas M, Easton DF, Milne RL, Chang-Claude J. Gene-environment interactions involving functional variants, Results from the Breast Cancer Association Consortium. Int J Cancer;141:1830–40, 2017.
  • Becker C. Prävention von Stürzen und sturzbedingten Verletzungen, Persönliche Bilanz und zukünftige Aufgaben [Prevention of falls and fall-related injuries : Personal balance and future tasks]. Z Gerontol Geriatr;50:672–5 2017.
  • Belharazem D, Grass A, Paul C, Vitacolonna M, Schalke B, Rieker RJ, Körner D, Jungebluth P, Simon-Keller K, Hohenberger P, Roessner EM, Wiebe K, Gräter T, Kyriss T, Ott G, Geserick P, Leverkus M, Ströbel P, Marx A. Increased cFLIP expression in thymic epithelial tumors blocks autophagy via NF-κB signalling. Oncotarget;8:89580–94 2017.
  • Bell GC, Caudle KE, Whirl-Carrillo M, Gordon RJ, Hikino K, Prows CA, Gaedigk A, Agundez J, Sadhasivam S, Klein TE, Schwab M. Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline for CYP2D6 genotype and use of ondansetron and tropisetron. Clin Pharmacol Ther;102:213–8 2017.
  • Beltrame JF, Crea F, Kaski JC, Ogawa H, Ong P, Sechtem U, Shimokawa H, Bairey Merz CN. International standardization of diagnostic criteria for vasospastic angina. Eur Heart J;38:2565–8 2017.
  • Bluhmki T, Peter RS, Rapp K, König H-H, Becker C, Lindlbauer I, Rothenbacher D, Beyersmann J, Büchele G. Understanding Mortality of Femoral Fractures Following Low-Impact Trauma in Persons With and Without Care Need. J Am Med Dir As-soc;18:221–6 2017.
  • Bonaros N, Petzina R, Cocchieri R, Jagielak D, Aiello M, Lapeze J, Laine M, Chocron S, Muir D, Eichinger W, Thielmann M, Labrousse L, Bapat V, Arne Rein K, Verhoye J-P, Gerosa G, Baumbach H, Kofler M, Bramlage P, Deutsch C, Thoenes M, Frank D, Romano M. Transaortic transcatheter aortic valve implantation as a first-line choice or as a last resort? An analysis based on the ROUTE registry. Eur J Cardiothorac Surg;51:919–26 2017.
  • Bouska A, Zhang W, Gong Q, Iqbal J, Scuto A, Vose J, Ludvigsen M, Fu K, Weisenburger DD, Greiner TC, Gascoyne RD, Rosenwald A, Ott G, Campo E, Rimsza LM, Delabie J, Jaffe ES, Braziel RM, Connors JM, Wu C-I, Staudt LM, D'Amore F, McKeithan TW, Chan WC. Combined copy number and mutation analysis identifies oncogenic pathways associated with transformation of follicular lymphoma. Leukemia;31:83–91 2017.
  • Bouska A, Bi C, Lone W, Zhang W, Kedwaii A, Heavican T, Lachel CM, Yu J, Ferro R, Eldorghamy N, Greiner TC, Vose J, Wei-senburger DD, Gascoyne RD, Rosenwald A, Ott G, Campo E, Rimsza LM, Jaffe ES, Braziel RM, Siebert R, Miles RR, Dave S, Reddy A, Delabie J, Staudt LM, Song JY, McKeithan TW, Fu K, Green M, Chan WC, Iqbal J. Adult High Grade B-cell Lympho-ma with Burkitt Lymphoma Signature: Genomic features and Potential Therapeutic Targets. Blood 2017.
  • Breitkopf-Heinlein K, Meyer C, König C, Gaitantzi H, Addante A, Thomas M, Wiercinska E, Cai C, Li Q, Wan F, Hellerbrand C, Valous NA, Hahnel M, Ehlting C, Bode JG, Müller-Bohl S, Klingmüller U, Altenöder J, Ilkavets I, Goumans M-J, Hawinkels LJAC, Lee S-J, Wieland M, Mogler C, Ebert MP, Herrera B, Augustin H, Sánchez A, Dooley S, Dijke P ten. BMP-9 interferes with liver regeneration and promotes liver fibrosis. Gut;66:939–54 2017.
  • Brosen K, Funck-Brentano C, Kroemer HK, Pirmohamed M, Schwab M. Open letter on access to the BIA 10-2474 clinical trial data. Lancet;389:156 2017.
  • Brouckaert O, Rudolph A, Laenen A, Keeman R, Bolla MK, Wang Q, Soubry A, Wildiers H, Andrulis IL, Arndt V, Beckmann MW, Benitez J, Blomqvist C, Bojesen SE, Brauch H, Brennan P, Brenner H, Chenevix-Trench G, Choi J-Y, Cornelissen S, Couch FJ, Cox A, Cross SS, Czene K, Eriksson M, Fasching PA, Figueroa J, Flyger H, Giles GG, González-Neira A, Guénel P, Hall P, Hollestelle A, Hopper JL, Ito H, Jones M, Kang D, Knight JA, Kosma V-M, Li J, Lindblom A, Lilyquist J, Lophatananon A, Mannermaa A, Manoukian S, Margolin S, Matsuo K, Muir K, Nevanlinna H, Peterlongo P, Pylkäs K, Saajrang S, Seynaeve C, Shen C-Y, Shu X-O, Southey MC, Swerdlow A, Teo S-H, Tollenaar RAEM, Truong T, Tseng C-C, van den Broek AJ, van Deurzen CHM, Winqvist R, Wu AH, Yip CH, Yu J-C, Zheng W, Milne RL, Pharoah PDP, Easton DF, Schmidt MK, Garcia-Closas M, Chang-Claude J, Lambrechts D, Neven P. Reproductive profiles and risk of breast cancer subtypes, A multi-center case-only study. Breast Cancer Res;19:119, 2017.
  • Büchele G, Becker C, Cameron ID, Auer R, Rothenbacher D, König HH, Rapp K. Fracture risk in people with developmental disabilities, Results of a large claims data analysis. Osteoporos Int;28:369–75 2017.
  • Cheng F, Twardowski L, Fehr S, Aner C, Schaeffeler E, Joos T, Knorpp T, Dorweiler B, Laufer S, Schwab M, Torzewski M. Selective p38alpha MAP kinase/MAPK14 inhibition in enzymatically modified LDL-stimulated human monocytes, Implications for atherosclerosis. FASEB J;31:674–86 2017.
  • Crea F, Bairey Merz CN, Beltrame JF, Kaski JC, Ogawa H, Ong P, Sechtem U, Shimokawa H, Camici PG. The parallel tales of microvascular angina and heart failure with preserved ejection fraction, A paradigm shift. Eur Heart J;38:473–7 2017.
  • Dai B, Grau M, Juilland M, Klener P, Höring E, Molinsky J, Schimmack G, Aukema SM, Hoster E, Vogt N, Staiger AM, Erdmann T, Xu W, Erdmann K, Dzyuba N, Madle H, Berdel WE, Trneny M, Dreyling M, Jöhrens K, Lenz P, Rosenwald A, Siebert R, Tzankov A, Klapper W, Anagnostopoulos I, Krappmann D, Ott G, Thome M, Lenz G. B-cell receptor-driven MALT1 activity regulates MYC signaling in mantle cell lymphoma. Blood;129:333–46 2017.
  • Day FR, Thompson DJ, Helgason H, Chasman DI, Finucane H, Sulem P, Ruth KS, Whalen S, Sarkar AK, Albrecht E, Altmaier E, Amini M, Barbieri CM, Boutin T, Campbell A, Demerath E, Giri A, He C, Hottenga JJ, Karlsson R, Kolcic I, Loh P-R, Lunetta KL, Mangino M, Marco B, McMahon G, Medland SE, Nolte IM, Noordam R, Nutile T, Paternoster L, Perjakova N, Porcu E, Rose LM, Schraut KE, Segrè AV, Smith AV, Stolk L, Teumer A, Andrulis IL, Bandinelli S, Beckmann MW, Benitez J, Bergmann S, Bochud M, Boerwinkle E, Bojesen SE, Bolla MK, Brand JS, Brauch H, Brenner H, Broer L, Brüning T, Buring JE, Campbell H, Catamo E, Chanock S, Chenevix-Trench G, Corre T, Couch FJ, Cousminer DL, Cox A, Crisponi L, Czene K, Davey Smith G, Geus EJCN de, Mutsert R de, Vivo I de, Dennis J, Devilee P, Dos-Santos-Silva I, Dunning AM, Eriksson JG, Fasching PA, Fernández-Rhodes L, Ferrucci L, Flesch-Janys D, Franke L, Gabrielson M, Gandin I, Giles GG, Grallert H, Gudbjartsson DF, Guénel P, Hall P, Hallberg E, Hamann U, Harris TB, Hartman CA, Heiss G, Hooning MJ, Hopper JL, Hu F, Hunter DJ, Ikram MA, Im HK, Järvelin M-R, Joshi PK, Karasik D, Kellis M, Kutalik Z, LaChance G, Lambrechts D, Langenberg C, Launer LJ, Laven JSE, Lenarduzzi S, Li J, Lind PA, Lindstrom S, Liu Y, Luan J'a, Mägi R, Mannermaa A, Mbarek H, McCarthy MI, Meisinger C, Meitinger T, Menni C, Metspalu A, Michailidou K, Milani L, Milne RL, Montgomery GW, Mulligan AM, Nalls MA, Navarro P, Nevanlinna H, Nyholt DR, Oldehinkel AJ, O'Mara TA, Padmanabhan S, Palotie A, Pedersen N, Peters A, Peto J, Pharoah PDP, Pouta A, Radice P, Rahman I, Ring SM, Robino A, Rosendaal FR, Rudan I, Rueedi R, Ruggiero D, Sala CF, Schmidt MK, Scott RA, Shah M, Sorice R, Southey MC, Sovio U, Stampfer M, Steri M, Strauch K, Tanaka T, Tikkanen E, Timpson NJ, Traglia M, Truong T, Tyrer JP, Uitterlinden AG, Edwards DRV, Vitart V, Völker U, Vollenweider P, Wang Q, Widen E, van Dijk KW, Willemsen G, Winqvist R, Wolffenbuttel BHR, Zhao JH, Zoledziewska M, Zygmunt M, Alizadeh BZ, Boomsma DI, Ciullo M, Cucca F, Esko T, Franceschini N, Gieger C, Gudnason V, Hayward C, Kraft P, Lawlor DA, Magnusson PKE, Martin NG, Mook-Kanamori DO, Nohr EA, Polasek O, Porteous D, Price AL, Ridker PM, Snieder H, Spector TD, Stöckl D, Toniolo D, Ulivi S, Visser JA, Völzke H, Wareham NJ, Wilson JF, Spurdle AB, Thorsteindottir U, Pollard KS, Easton DF, Tung JY, Chang-Claude J, Hinds D, Murray A, Murabito JM, Stefansson K, Ong KK, Perry JRB. Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk. Nat Genet;49:834–41. 2017.
  • De Hoogt R, Estrada M, Vidic S, Davies E, Osswald A, Barbier M, Espirito Santo V, Gjerde K, van Zoggel H, Blom S, Dong M, Närhi K, Boghaert E, Brito C, Chong Y, Sommergruber W, van der Kuip H, van Weerden W, Verschuren E, Hickman J, Graeser R. Protocols and characterization data for 2D, 3D, and slice-based tumor models from the PREDECT project. Sci Data 2017. accepted for publication.
  • Drenberg CD, Gibson AA, Pounds SB, Shi L, Rhinehart DP, Li L, Hu S, Du G, Nies AT, Schwab M, Pabla N, Blum W, Gruber TA, Baker SD, Sparreboom A. OCTN1 Is a High-Affinity Carrier of Nucleoside Analogues. Cancer Res;77:2102–11 2017.
  • Erdmann T, Klener P, Lynch JT, Grau M, Vočková P, Molinsky J, Tuskova D, Hudson K, Polanska UM, Grondine M, Mayo M, Dai B, Pfeifer M, Erdmann K, Schwammbach D, Zapukhlyak M, Staiger AM, Ott G, Berdel WE, Davies BR, Cruzalegui F, Trneny M, Lenz P, Barry ST, Lenz G. Sensitivity to PI3K and AKT inhibitors is mediated by divergent molecular mechanisms in subtypes of DLBCL. Blood;130:310–22 2017.
  • European Society of Gastrointestinal Endoscopy (ESGE) and European Association for the Study of the Liver (EASL) Clinical Guideline. Role of endoscopy in primary sclerosing cholangitis. J Hepatol;66:1265–81 2017.
  • Finkelmeier F, Sturm C, Friedrich-Rust M, Bojunga J, Sarrazin C, Tal A, Hausmann J, Zeuzem S, Zangos S, Albert J, Farnik H. Predictive Value of Computed Tomography Scans and Clinical Findings for the Need of Endoscopic Necrosectomy in Walled-off Necrosis From Pancreatitis. Pancreas;46:1039–45 2017.
  • Florian MC, Klenk J, Marka G, Soller K, Kiryakos H, Peter R, Herbolsheimer F, Rothenbacher D, Denkinger M, Geiger H. Ex-pression and Activity of the Small RhoGTPase Cdc42 in Blood Cells of Older Adults Are Associated With Age and Cardiovascular Disease. J Gerontol A Biol Sci Med Sci;72:1196–200 2017.
  • Fritz P, Kleinhans A, Kuisle F, Albu P, Fritz-Kuisle C, Alscher MD. Medical diagnosis as a linguistic game. BMC Med Inform Decis Mak;17:103 2017.
  • Gidal BE, Mintzer S, Schwab M, Schutz R, Kharidia J, Blum D, Grinnell T, Sunkaraneni S. Evidence for a pharmacokinetic interaction between eslicarbazepine and rosuvastatin, Potential effects on xenobiotic transporters. Epilepsy Res;135:64–70 2017.
  • Giné-Garriga M, Coll-Planas L, Guerra M, Domingo À, Roqué M, Caserotti P, Denkinger M, Rothenbacher D, Tully MA, Kee F, McIntosh E, Martín-Borràs C, Oviedo GR, Jerez-Roig J, Santiago M, Sansano O, Varela G, Skjødt M, Wirth K, Dallmeier D, Klenk J, Wilson JJ, Blackburn NE, Deidda M, Lefebvre G, González D, Salvà A. The SITLESS project, Exercise referral schemes enhanced by self-management strategies to battle sedentary behaviour in older adults: study protocol for a randomised controlled trial. Trials;18:221 2017.
  • Goebel N, Bonte D, Salehi-Gilani S, Nagib R, Ursulescu A, Franke UFW. Minimally Invasive Access Aortic Arch Surgery. Inno-vations (Phila) 2017.
  • Greulich S, Kaesemann P, Seitz A, Birkmeier S, Abu-Zaid E, Vecchio F, Sechtem U, Mahrholdt H. Effects of caffeine on the detection of ischemia in patients undergoing adenosine stress cardiovascular magnetic resonance imaging. J Cardiovasc Magn Reson;19:103 2017.
  • Greulich S, Mayr A, Kitterer D, Latus J, Henes J, Steubing H, Kaesemann P, Patrascu A, Greiser A, Groeninger S, Braun N, Alscher MD, Sechtem U, Mahrholdt H. T1 and T2 mapping for evaluation of myocardial involvement in patients with ANCA-associated vasculitides. J Cardiovasc Magn Reson;19:6 2017.
  • Greulich S, Mayr A, Kitterer D, Latus J, Henes J, Vecchio F, Kaesemann P, Patrascu A, Greiser A, Groeninger S, Romeo F, Braun N, Alscher MD, Sechtem U, Mahrholdt H. Advanced myocardial tissue characterisation by a multi-component CMR protocol in patients with rheumatoid arthritis. Eur Radiol 2017.
  • Guberina M, Eberhardt W, Stuschke M, Gauler T, Heinzelmann F, Cheufou D, Kimmich M, Friedel G, Schmidberger H, Dar-wiche K, Jendrossek V, Schuler M, Stamatis G, Pöttgen C. Heart dose exposure as prognostic marker after radiotherapy for resectable stage IIIA/B non-small-cell lung cancer, Secondary analysis of a randomized trial. Ann Oncol;28:1084–9 2017.
  • Häberle L, Hein A, Rübner M, Schneider M, Ekici AB, Gass P, Hartmann A, Schulz-Wendtland R, Beckmann MW, Lo W-Y, Schroth W, Brauch H, Fasching PA, Wunderle M. Predicting Triple-Negative Breast Cancer Subtype Using Multiple Single Nucleotide Polymorphisms for Breast Cancer Risk and Several Variable Selection Methods. Geburtshilfe Frauenheilkd;77:667–78. 2017.
  • Hausmann J, Schmelz R, Walldorf J, Filmann N, Zeuzem S, Albert JG. Pan-intestinal capsule endoscopy in patients with postoperative Crohn's disease, A pilot study. Scand J Gastroenterol;52:840–5 2017.
  • Heidrich K, Thiede C, Schäfer-Eckart K, Schmitz N, Aulitzky WE, Krämer A, Rösler W, Hänel M, Einsele H, Baldus CD, Trappe RU, Stölzel F, Middeke JM, Röllig C, Taube F, Kramer M, Serve H, Berdel WE, Ehninger G, Bornhäuser M, Schetelig J. Alloge-neic Hematopoietic Cell Transplantation in Intermediate Risk Acute Myeloid Leukemia negative for FLT3-ITD, NPM1- or biallelic CEBPA Mutations. Ann Oncol 2017. (Klinische Studien/Case Reports).
  • Helbostad JL, Vereijken B, Becker C, Todd C, Taraldsen K, Pijnappels M, Aminian K, Mellone S. Mobile Health Applications to Promote Active and Healthy Ageing. Sensors (Basel);17 2017.
  • Hochhaus A, Larson RA, Guilhot F, Radich JP, Branford S, Hughes TP, Baccarani M, Deininger MW, Cervantes F, Fujihara S, Ortmann C-E, Menssen HD, Kantarjian H, O'Brien SG, Druker BJ. Long-Term Outcomes of Imatinib Treatment for Chronic Myeloid Leukemia. N Engl J Med;376:917–27 2017. (Klinische Studien/Case Reports).
  • Höring E, Montraveta A, Heine S, Kleih M, Schaaf L, Vöhringer MC, Esteve-Arenys A, Roué G, Colomer D, Campo E, Ott G, Aulitzky WE, van der Kuip H. Dual targeting of MCL1 and NOXA as effective strategy for treatment of mantle cell lymphoma. Br J Haematol;177:557–61 2017.
  • Iafrancesco M, Goebel N, Mascaro J, Franke UFW, Pacini D, Di Bartolomeo R, Weiss G, Grabenwöger M, Leontyev SA, Mohr F-W, Sioris T, Jakob H, Tsagakis K. Aortic diameter remodelling after the frozen elephant trunk technique in aortic dissec-tion, Results from an international multicentre registry. Eur J Cardiothorac Surg;52:310–8 2017.
  • Jeske J, Bitter A, Thasler WE, Weiss TS, Schwab M, Burk O. Ligand-dependent and -independent regulation of human hepatic sphingomyelin phosphodiesterase acid-like 3A expression by pregnane X receptor and crosstalk with liver X receptor. Biochem Pharmacol;136:122–35 2017.
  • Jeske J, Windshugel B, Thasler WE, Schwab M, Burk O. Human pregnane X receptor is activated by dibenzazepine carba-mate-based inhibitors of constitutive androstane receptor. Arch Toxicol;91:2375–90 2017.
  • Jiao X, Aravidis C, Marikkannu R, Rantala J, Picelli S, Adamovic T, Liu T, Maguire P, Kremeyer B, Luo L, Holst S v., Kontham V, Thutkawkorapin J, Margolin S, Du Q, Lundin J, Michailidou K, Bolla MK, Wang Q, Dennis J, Lush M, Ambrosone CB, Andrulis IL, Anton-Culver H, Antonenkova NN, Arndt V, Beckmann MW, Blomqvist C, Blot W, Boeckx B, Bojesen SE, Bonanni B, Brand JS, Brauch H, Brenner H, Broeks A, Brüning T, Burwinkel B, Cai Q, Chang-Claude J, Couch FJ, Cox A, Cross SS, Deming-Halverson SL, Devilee P, Dos-Santos-Silva I, Dörk T, Eriksson M, Fasching PA, Figueroa J, Flesch-Janys D, Flyger H, Gabrielson M, García-Closas M, Giles GG, González-Neira A, Guénel P, Guo Q, Gündert M, Haiman CA, Hallberg E, Hamann U, Harrington P, Hooning MJ, Hopper JL, Huang G, Jakubowska A, Jones ME, Kerin MJ, Kosma V-M, Kristensen VN, Lambrechts D, Le Marchand L, Lubinski J, Mannermaa A, Martens JWM, Meindl A, Milne RL, Mulligan AM, Neuhausen SL, Nevanlinna H, Peto J, Pylkäs K, Radice P, Rhenius V, Sawyer EJ, Schmidt MK, Schmutzler RK, Seynaeve C, Shah M, Simard J, Southey MC, Swerdlow AJ, Truong T, Wendt C, Winqvist R, Zheng W, Benitez J, Dunning AM, Pharoah PDP, Easton DF, Czene K, Hall P, Lindblom A. PHIP - a novel candidate breast cancer susceptibility locus on 6q14.1. Oncotarget;8:102769–82, 2017.
  • Kaier K, Kampen F v., Baumbach H, Zur Mühlen C v., Hehn P, Vach W, Zehender M, Bode C, Reinöhl J. Two-year post-discharge costs of care among patients treated with transcatheter or surgical aortic valve replacement in Germany. BMC Health Serv Res;17:473 2017.
  • Kamman AV, Jonker FHW, Sechtem U, Harris KM, Evangelista A, Montgomery DG, Patel HJ, Eagle KA, Trimarchi S. Predictors of Stable Aortic Dimensions in Medically Managed Acute Aortic Syndromes. Ann Vasc Surg;42:143–9 2017.
  • Kampe K, Kohler M, Albrecht D, Becker C, Hautzinger M, Lindemann U, Pfeiffer K. Hip and pelvic fracture patients with fear of falling, Development and description of the "Step by Step" treatment protocol. Clin Rehabil;31:571–81 2017.
  • Kastner S, Becker C, Lindemann U. High Intensity Functional Exercise (HIFE) Training. Physiosci;13:109–16 2017.
  • Kitterer D, Biegger D, Segerer S, Braun N, Alscher MD, Latus J. Alteration of membrane complement regulators is associated with transporter status in patients on peritoneal dialysis. PLoS ONE;12:e0177487 2017.
  • Kitterer D, Segerer S, Braun N, Alscher MD, Latus J. Gender-Specific Differences in Peritoneal Dialysis. Kidney Blood Press Res;42:276–83 2017.
  • Klein HH, Sechtem U, Trappe H-J. Fitness to Drive in Cardiovascular Disease. Dtsch Arztebl Int;114:692–702 2017.
  • Klenk J, Becker C, Palumbo P, Schwickert L, Rapp K, Helbostad JL, Todd C, Lord SR, Kerse N. Conceptualizing a Dynamic Fall Risk Model Including Intrinsic Risks and Exposures. J Am Med Dir Assoc;18:921–7 2017.
  • Klingel K, Sechtem U, Kindermann I. Myokardbiopsie. Der Kardiologe;11:227–46 2017.
  • Kofler M, Reinstadler SJ, Stastny L, Dumfarth J, Reindl M, Wachter K, Rustenbach CJ, Müller S, Feuchtner G, Friedrich G, Metzler B, Grimm M, Bonaros N, Baumbach H. EuroSCORE II and the STS score are more accurate in transapical than in transfemoral transcatheter aortic valve implantation. Interact Cardiovasc Thorac Surg 2017.
  • Krauss M, Hofmann U, Schafmayer C, Igel S, Schlender J, Mueller C, Brosch M, Schoenfels W v., Erhart W, Schuppert A, Block M, Schaeffeler E, Boehmer G, Goerlitz L, Hoecker J, Lippert J, Kerb R, Hampe J, Kuepfer L, Schwab M. Translational learning from clinical studies predicts drug pharmacokinetics across patient populations. npj Syst Biol Appl;3:11 2017.
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  • Ott G. Aggressive B-cell lymphomas in the update of the 4th edition of the World Health Organization classification of haematopoietic and lymphatic tissues: refinements of the classification, new entities and genetic findings. Br J Haematol;178:871–87 2017.
  • Ott G, Delabie J, Gascoyne RD, Campo E, Stein H, Jaffe ES. T-cell/histiocyte-rich large B-cell lymphoma. In: Swerdlow SH, Campo E, Harris NL, Jaffe ES, Pileri SA, Stein H, Thiele J et al. (Eds.). WHO classification of tumours of haematopoietic and lymphoid tissues. IARC, Lyon 2017; Revised 4th edition:298–9 2017.
  • Pfeiffer K. Depression bei pflegenden Angehörigen. In: Fellgiebel A, Hautzinger M (Hrsg.). Handbuch Altersdepression. Springer, Heidelberg 2017.
  • Pfeiffer K. Depression nach Schlaganfall. In: Fellgiebel A, Hautzinger M (Hrsg.). Handbuch Altersdepression. Springer, Heidelberg 2017.
  • Raddatz A, Iseke, K.-B., Oleimeulen, U., Pommer, W., Alscher, M. D., Birk, H.-W., Gloy, J., Heuer, U., Kitsche, B., Pfab, T. Assistierte Dialyse – eine Perspektive für Deutschland. Welt der Krankenversicherung;6:210–6 2017.
  • Rufa M, Ursulescu A, Stan A, Albert M, Baumbach H, Franke UFW. Minimally Invasive Surgery for Aortic Aneurysms. In: Ion Tintoiu, Adrian Ursulescu, John A. Elefteriades, Malcolm John Underwood, Ionel Droc (eds.). Chapter 63. Surgical Treatment of Acute Aortic Syndrome. New Approaches to Aortic Disease from Valve to Abdominal Bifurcation. Elsevier 2017.
  • Ryu CS, Klein K, Zanger UM. Membrane Associated Progesterone Receptors, Promiscuous Proteins with Pleiotropic Functions - Focus on Interactions with Cytochromes P450. Front Pharmacol;8:159 2017.
  • Schanz M. Hyperkaliämie - Ursachen und Behandlung. Dialyse aktuell;21:181–7 2017.
  • Schanz M KM. Immunologische Serumdiagnostik. In:, Alscher MD (ed.). Nephrologie konkret. Thieme Verlag 2017. in press.
  • Schanz M. Morbus Behcet. In, Alscher MD (ed.). Nephrologie konkret. Thieme Verlag 2017. in press.
  • Schanz M. Nephrogene systemische Fibrose. In, Alscher MD (ed.). Nephrologie konkret. Thieme Verlag 2017. in press.
  • Schanz M KM. Retroperitoneale Fibrose. In:, Alscher MD (ed.). Nephrologie konkret. Thieme Verlag 2017. in press.
  • Schanz M KM. Tumorlysesyndrom. In:, Alscher MD (ed.). Nephrologie konkret. Thieme Verlag 2017. in press.
  • Schricker S. Veränderungen der Harnstoffkonzentration im Serum. In:, Alscher MD (ed.). Nephrologie konkret. Thieme Verlag 2017. in press.
  • Schricker S, Alscher MD. Nephrokalzinose. In, Alscher MD (ed.). Nephrologie konkret. Thieme Verlag 2017. in press.
  • Schricker S, Alscher MD. Obstruktive Nephropathie. In, Alscher MD (ed.). Nephrologie konkret. Thieme Verlag 2017. in press.
  • Schricker S, Alscher MD. Zystinose. In, Alscher MD (ed.). Nephrologie konkret. Thieme Verlag 2017. in press.
  • Schwab M, Billing H, Mörike K. Drug Use, Dosing, and Toxicity in Renal Disease. In:, Denis F. Geary and Franz Schaefer (eds.). Pediatric Kidney Disease. 2nd edition, Chapter 70 in Section 14: Nephrotoxicity and Pharmacotherapy. Springer Science + Business Media 2017.
  • Ursulescu A, Stan A, Rufa M, Göbel N, Albert M, Franke UFW. Minimally Invasive Ross Procedure. In: Ion Tintoiu, Adrian Ursulescu, John A. Elefteriades, Malcolm John Underwood, Ionel Droc (eds.). Chapter 64. Surgical Treatment of Acute Aortic Syndrome. New Approaches to Aortic Disease from Valve to Abdominal Bifurcation. Elsevier 2017.
  • Weiß H. Einführung und einige persönliche Erinnerungen. In: Weiß, H., Rumpeltes, R. (Hrsg.). Hanna Segal Revisited. Zur Aktualität ihres Werkes. Frankfurt a.M.: Brandes & Apsel:7–27 2017.
  • Weiß H. Primitive Wiedergutmachung, Wiederholungszwang und unbewusste Verarbeitung von Schuld. In Leuzinger-Bohleber, M., Arnold, S. Solms, M. (Hg.). Das Unbewusste. Eine Brücke zwischen Psychoanalyse und Neurowissenschaften. Göttingen: Vandenhoeck & Ruprecht:129–42 2017.
  • Weiß H. Reflections on primitive reparation, the repetition compulsion and the unconscious processing of guilt. In: Leuzinger-Bohleber, M., Arnold, S., Solms, M. (Hg.). The unconscious. A bridge between psychoanalysis and cognitive neuroscience. London, New York: Routledge:81–9 2017.
  • Wilz G, Pfeiffer K. Psychotherapie mit älteren pflegenden Angehörigen [Psychotherapy with older caregivers]. Nervenarzt;88:1246–51 2017.
  • Wirth K, Klenk J, Brefka S, Dallmeier D, Faehling K, Roqué I Figuls M, Tully MA, Giné-Garriga M, Caserotti P, Salvà A, Rothenbacher D, Denkinger M, Stubbs B. Biomarkers associated with sedentary behaviour in older adults, A systematic review. Ageing Res Rev;35:87–111 2017.
  • Wolke H. Bleinephropathie. In:, Alscher MD (ed.). Nephrologie konkret. Thieme Verlag 2017. in press.
  • Wolke H. Cadmiumnephropathie. In:, Alscher MD (ed.). Nephrologie konkret. Thieme Verlag 2017. in press.
  • Wolke H. Chronische Beckenschmerzsyndrom. In:, Alscher MD (ed.). Nephrologie konkret. Thieme Verlag 2017. in press.
  • Wolke H. Dysurie. In:, Alscher MD (ed.). Nephrologie konkret. Thieme Verlag 2017. in press.
  • Wolke H. Goldnephropathie. In:, Alscher MD (ed.). Nephrologie konkret. Thieme Verlag 2017. in press.
  • Wolke H. Lithiumnephropathie. In:, Alscher MD (ed.). Nephrologie konkret. Thieme Verlag 2017. in press.
  • Wolke H. Penicillaminnephropathie. In:, Alscher MD (ed.). Nephrologie konkret. Thieme Verlag 2017. in press.
  • Wolke H. Polyurie. In:, Alscher MD (ed.). Nephrologie konkret. Thieme Verlag 2017. in press.
  • Wolke H. Sonographie in der Peritonealdialyse. Nieren- und Hochdruckkrankheiten;46:219–22 2017.
  • Wolke H. TINU. In:, Alscher MD (ed.). Nephrologie konkret. Thieme Verlag 2017. in press.
  • Yu A-M, Ingelman-Sundberg M, Cherrington NJ, Aleksunes LM, Zanger UM, Xie W, Jeong H, Morgan ET, Turnbaugh PJ, Klaassen CD, Bhatt AP, Redinbo MR, Hao P, Waxman DJ, Wang L, Zhong X-B. Regulation of drug metabolism and toxicity by multiple factors of genetics, epigenetics, lncRNAs, gut microbiota, and diseases, A meeting report of the 21st International Symposium on Microsomes and Drug Oxidations (MDO). Acta Pharm Sin B;7:241–8 2017.
  • Auffray C*, Caulfield T, Khoury MJ*, Lupski JR*, Schwab M, Veenstra T. Genome Medicine, Past, present and future. Genome Med;3:6 2011.
  • Auffray C, Caulfield T, Khoury MJ*, Lupski JR*, Schwab M, Veenstra T. Looking back at genomic medicine in 2011. Genome Med;4:9 2012.
  • Auffray C, Caulfield T, Khoury MJ*, Lupski JR*, Schwab M, Veenstra T. 2012 highlights in translational 'omics. Genome Med;5:10 2013.
  • Auffray C, Caulfield T, Griffin JL, Khoury MJ, Lupski JR, Schwab M. From genomic medicine to precision medicine, Highlights of 2015. Genome Med;8:12 2016.
  • Brauch H, Schroth W, Goetz MP, Murdter TE, Winter S, Ingle JN, Schwab M, Eichelbaum M. Reply to A.-S. Dieudonne et al and J.M. Rae et al. J Clin Oncol;31:2755–6 2013.
  • Brauch H, Schwab M. CYP2D6 genotyping and tamoxifen in the treatment of post-menopausal breast cancer - a reply. Br J Clin Pharmacol;78:433–4 2014.
  • Burk O, Schwab M. The limited impact of CYP3A5 genotype for the pharmacokinetics of CYP3A substrates. Eur J Clin Pharmacol;63:1097–8 2007.
  • Cascorbi I, Schwab M. Epigenetics in Drug Response. Clin Pharmacol Ther;99:468–70 2016.
  • Danesi R, Del Re M, Ciccolini J, Schellens JHM, Schwab M, van Schaik RHN, van Kuilenburg ABP. Prevention of fluoropyrimidine toxicity: do we still have to try our patient's luck? Ann Oncol;28:183 2017.
  • Fisel P, Nies AT, Schaeffeler E, Schwab M. The importance of drug transporter characterization to precision medicine. Expert Opin Drug Metab Toxicol;13:361–5 2017.
  • Geisler T, Bigalke B, Schwab M. CYP2C19 Genotype and Outcomes of Clopidogrel Treatment. N Engl J Med;364:481–2 2011.
  • Gleiter CH, Bucheler R, Schwab M. Letter to the editor concerning Ufer et al., Eur J Clin Pharmacol 58:779-783 (2003). Eur J Clin Pharmacol;59:491–4 2003.
  • Herrlinger KR, Schwab M, Fellermann K, Stange EF. 6-thioguanine-buried alive? Gastroenterol;126:940–1 2004.
  • Jeck N, Waldegger S, Wissinger B, Schwab M, Lang F. Response, ClC-Kb Mutation Revisited. Hypertension 2006.
  • Klotz U, Treiber G, Schwab M. Determinants of non-response in Helicobacter pylori eradication trials. J Gastroenterol Hepatol;20:1471 2005.
  • Lang T, Schroth W, Brauch H, Schwab M. ABCC2 and clinical outcome of tamoxifen therapy. J Clin Oncol;28:e448 2010.
  • Morike K, Boesen N, Mikus G, Schwab M. Drug therapy information, A service provided by clinical pharmacologists for physicians in private practice and hospitals. Eur J Clin Pharmacol;54:573–4 1998.
  • Pawel J v., Schwab M, Sehrt D. Annual meeting of CESAR in Tuebingen, Germany June 27-29, 2013. Int J Clin Pharmacol Ther;52:73 2014.
  • Pazzagli M, Brandslund I, Vermeersch P, die Resta C, Marc J, van Schaik R, Schwab M. Focus on the activities of the joint EFLM-ESPT Working Group on Personalized Laboratory Medicine (WG-PLM). IFCC eNews;September - October:18–9 2015.
  • Province MA, Klein TE. Re, CYP2D6 genotyping and the use of tamoxifen in breast cancer. J Natl Cancer Inst;106:djt379 2014.
  • Schroth W, Schwab M, Brauch H. Association between CYP2D6 Polymorphisms and Breast Cancer Outcomes, Author's Re-play. JAMA;303:517 2010.
  • Schwab M. Reply zu Croucher PJ, Mascheretti S, Foelsch UR, Hampe J, Schreiber S. Lack of association between the C3435T MDR1 gene polymorphism and inflammatory bowel disease in two independent Northern European populations. Gastroenterol;125:1920–1 2003.
  • Schwab M. Reply zu 'Glas et al. MDR1 gene polymorphism in ulcerative colitis' und 'Gazouli et al. The C3435T MDR1 gene polymorphism is not associated with susceptibility for ulcerative colitis in Greek population.'. Gastroenterol;126:369 2004.
  • Schwab M. Reply to "Thiopurine treatment in inflammatory bowel disease". Clin Pharmacokinet;46:805 2007.
  • Schwab M. Kommentar zu, TNF-á und chronisch-obstruktive Lungenerkrankung. Der TNF-á Anitkörper Infliximab ist bei COPD unwirksam. Pneumo News;1:26 2008.
  • Schwab M. Kommentar zu, Chronisch obstruktive Lungenerkrankung. Senkt Salmeterol + Fluticason die Mortalität? Pneumo News;2:14 2008.
  • Schwab M. Kommentar zu, Asthma bronchiale: Besteht ein klinischer Nutzen einer anti-Interleukin-5-Antikörpertherapie (Mepolizumab)? Pneumo News;6:31 2008.
  • Schwab M*, Kuhls E. Neonatal morbidity and mortality associated with maternal haemolysis, elevated liver enzymes and low platelets syndrome--the impact of neutropenia. Eur. J Pediatr;157:439–40 1998.
  • Schwab M, Kaschka WP, Spina E. Preface. In, Schwab M, Kaschka WP, Spina E (eds.). Pharmacogenomics in Psychiatry. Adv Biolog Psychiatr;25:VI–VII 2010.
  • Schwab M, Böswald M. Die transitorische Hyperphosphatasämie im Kindesalter. Pädiat Prax;54:206 1998.
  • Schwab M*, Fisel P, Schäffeler E. Metabolomik und Tumorerkrankungen [Metabolomics and Cancer]. Der Pathologe 2017.
  • Schwab J, Gottwik M, Schwab M, Fischer-Bosch M. [Comment on the contribution, A. Hagendorff et al., Loffler fibroplastic endocarditis in the thrombotic stage in isolated right ventricular tissue eosinophilia]. Z Kardiol;87:644 1998.
  • Schwab M, Moerike K. Antiarrhythmic drug treatment after cardioversion of atrial fibrillation. Lancet;380:1467 2012.
  • Schwab M, Ruder H. Hyponatraemia and cerebral convulsion due to DDAVP administration in patients with enuresis nocturna or urine concentration testing. Eur. J Pediatr;156:668 1997.
  • Schwab M, Schaeffeler E. Warfarin pharmacogenetics meets clinical use. Blood;118:2938–9 2011.
  • Schwab M, Schaeffeler E. Pharmacogenomics, A key component of personalized therapy. Genome Med;4:93 2012.
  • Teichgraber U, Atreya I, Atreya R, Schwab M, Neurath MF. Infliximab treatment induces levels of the active azathioprine metabolite TGTP in Crohn's disease. Inflamm Bowel Dis;19:E54-E55 2013.
  • Zanger UM, K K, Schwab M. In Reply, Is 5-FU-induced severe toxicity in DPYD*2A individuals related to gender or to treat-ment regimen?" by Maarten J. Deenen, et. al. J Clin Oncol;26:4998 2008.
  • Zanger UM, Schwab M, Raimundo S, Toscano C, Eichelbaum M. Reply zu Gaedigk et al "Limited association of the 2988G>A SNP with CYP2D6*41 in African Americans.". Clin Pharmacol Ther;77:230–1 2005.
Habilitations
  • Kimmel, Martin
    Biomarkers of Acute Kidney Injury. Universität Tübingen
  • Danielyan, Lusine
    Erythropoietin als zytoprotektiver Faktor bei Hypoxie-assoziierter Erkrankungen: die Rolle in regenerativer Medizin. Universität Tübingen

PHD/MD Theses


  • Kunkel, Jasmin
    Systematische Analyse antimikrobieller Histone des Kolon, Universität Hohenheim
  • Gruber, Kim
    Molekulare Diagnostik und Analyse von Tyrosinkinasen für eine individualisierte Therapie primärer Adenokarzinome der Lunge, Universität Tübingen
  • Neul, Claudia
    Identifikation und funktionelle Charakterisierung pharmakologischer Wirkstoffe für die organi-schen Kationentransporter SLC22A1, -A2, -A3 und SLC47A1, Mathematisch-Naturwissenschaftliche Fakultät der Eberhard Karls Universität Tübingen


Master Theses


  • Meyerhoff, Carolin
    Targeted amplicon sequencing for validation of recurrent mutations in mantle cell lymphoma. Masterarbeit im Studiengang Molekulare Medizin der Universität Ulm
  • Bollgönn, Elena
    Parakrine Kommunikation zwischen Tumorzellen und Fibroblasten kolorektaler Karzinome: Untersuchung zum Einfluss des K-Ras Status. Fakultät für Energie-, Verfahrens- und Bio-technik, Universität Stuttgart


Bachelor


  • Scharpf, Janika
    Etablierung einer quantitativen immunhistochemischen Methode zum Nachweis der Kern-rezeptoren PXR und CAR; Fakultät Medical and Life Sciences, Hochschule Furtwangen