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Publications 2016 (IKP + RBK)

  • Albrecht, D.; Pendergrass, A.; Becker, C.; Hautzinger, M.; Pfeiffer, K.: Interventionsstudien zur Unterstutzung hauslicher Pflege. Z Gerontol Geriatr, 2016.
  • Albrecht, Diana; Wollensak, Tanja; Ernst, Christian; Becker, Clemens; Hautzinger, Martin; Pfeiffer, Klaus: Costs of informal care in a sample of German geriatric stroke survivors. Eur J Ageing, 13 (1), S. 49–61, 2016.
  • Arlanov, R.; Lang, T.; Jedlitschky, G.; Schaeffeler, E.; Ishikawa, T.; Schwab, M.; Nies, A. T.: Functional characterization of common protein variants in the efflux transporter ABCC11 and identification of T546M as functionally damaging variant. Pharmacogenomics J, 16 (2), S. 193–201, 2016.
  • Atreya, I.; Diall, A.; Dvorsky, R.; Atreya, R.; Henninger, C.; Grun, M. et al.: Designer Thiopurine-analogues for Optimised Immunosuppression in Inflammatory Bowel Diseases. In: J Crohns Colitis 10 (10), S. 1132–1143, 2016.
  • Baumbach, Hardy; Ahad, Samir; Rustenbach, Christian; Hill, Stephan; Schaufele, Tim; Wachter, Kristina; Franke, Ulrich Friedrich Wilhelm: Conventional versus Transapical Aortic Valve Replacement: Is It Time for Shift in Indications? Thorac Cardiovasc Surg, 2016.
  • Baumbach, Hardy; Ahad, Samir; Hill, Stephan; Schaufele, Tim; Adili, Sara; Wachter, Kristina; Franke, Ulrich F. W.: Transaortic Transcatheter Aortic Valve Implantation and Concomitant Off Pump Revascularization. Innovations (Phila), 11 (5), S. 363–366, 2016.
  • Becker, Svetlana; Florian, Anca; Patrascu, Alexandru; Rosch, Sabine; Waltenberger, Johannes; Sechtem, Udo et al.: Identification of cardiomyopathy associated circulating miRNA biomarkers in patients with muscular dystrophy using a complementary cardiovascular magnetic resonance and plasma profiling approach. J Cardiovasc Magn Reson, 18 (1), S. 25, 2016.
  • Bell, Gillian C.; Caudle, Kelly E.; Whirl-Carrillo, Michelle; Gordon, Ronald J.; Hikino, Keiko; Prows, Cynthia A. et al.: Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 Genotype and Use of Ondansetron and Tropisetron. Clin Pharmacol Ther, 2016.
  • Beltrame, John F.; Crea, Filippo; Kaski, Juan Carlos; Ogawa, Hisao; Ong, Peter; Sechtem, Udo et al.: The Who, What, Why, When, How and Where of Vasospastic Angina. Circ J, 80 (2), S. 289–298, 2016.
  • Benzinger, Petra; Becker, Clemens; Todd, Chris; Bleibler, Florian; Rothenbacher, Dietrich; Konig, Hans-Helmut; Rapp, Kilian: The impact of preventive measures on the burden of femoral fractures - a modelling approach to estimating the impact of fall prevention exercises and oral bisphosphonate treatment for the years 2014 and 2025. BMC Geriatr, 16, S. 75, 2016.
  • Blank, A.; Markert, C.; Hohmann, N.; Carls, A.; Mikus, G.; Lehr, T. et al.: First-in-human application of the novel hepatitis B and hepatitis D virus entry inhibitor myrcludex B. In: J Hepatol 65 (3), S. 483–489, 2016.
  • Bluhmki, Tobias; Peter, Raphael Simon; Rapp, Kilian; Konig, Hans-Helmut; Becker, Clemens; Lindlbauer, Ivonne et al.: Understanding Mortality of Femoral Fractures Following Low-Impact Trauma in Persons With and Without Care Need. J Am Med Dir Assoc, 2016.
  • Bognar, M. K.; Vincendeau, M.; Erdmann, T.; Seeholzer, T.; Grau, M.; Linnemann, J. R. et al.: Oncogenic CARMA1 couples NF-kappaB and beta-catenin signaling in diffuse large B-cell lymphomas. Oncogene, 35 (32), S. 4269–4281, 2016.
  • Bogomolov, P.; Alexandrov, A.; Voronkova, N.; Macievich, M.; Kokina, K.; Petrachenkova, M. et al.: Treatment of chronic hepatitis D with the entry inhibitor myrcludex B: First results of a phase Ib/IIa study. In: J Hepatol 65 (3), S. 490–498, 2016.
  • Bouska, A.; Zhang, W.; Gong, Q.; Iqbal, J.; Scuto, A.; Vose, J. et al.: Combined copy number and mutation analysis identifies oncogenic pathways associated with transformation of follicular lymphoma. Leukemia, 2016.
  • Brosen, K.; Funck-Brentano, C.; Kroemer, H. K.; Pirmohamed, M.; Schwab, M.: Open letter on access to the BIA 10-2474 clinical trial data. In: Lancet, 2016.
  • Buchele, G.; Becker, C.; Cameron, I. D.; Auer, R.; Rothenbacher, D.; Konig, H. H.; Rapp, K.: Fracture risk in people with developmental disabilities: results of a large claims data analysis. Osteoporos Int, 2016.
  • Buchele, Gisela; Rapp, Kilian; Konig, Hans-Helmut; Jaensch, Andrea; Rothenbacher, Dietrich; Becker, Clemens; Benzinger, Petra: The Risk of Hospital Admission Due to Traumatic Brain Injury Is Increased in Older Persons With Severe Functional Limitations. J Am Med Dir Assoc, 17 (7), S. 609–612, 2016.
  • Bueno, Hector; Sinnaeve, Peter; Annemans, Lieven; Danchin, Nicolas; Licour, Muriel; Medina, Jesus et al.: Opportunities for improvement in anti-thrombotic therapy and other strategies for the management of acute coronary syndromes: Insights from EPICOR, an international study of current practice patterns. Eur Heart J Acute Cardiovasc Care, 5 (1), S. 3–12, 2016.
  • Bures, Maximilian; Hoffler, Hans-Klaus; Friedel, Godehard; Kyriss, Thomas; Boedeker, Enole; Langer, Florian et al.: Albumin-glutaraldehyde glue for repair of superficial lung defect: an in vitro experiment. J Cardiothorac Surg, 11 (1), S. 63, 2016.
  • Cascorbi, I.; Schwab, M.: Epigenetics in Drug Response. Clin Pharmacol Ther, 99 (5), S. 468–470, 2016.
  • Cheng, Timothy H. T.; Thompson, Deborah; Painter, Jodie; O'Mara, Tracy; Gorman, Maggie; Martin, Lynn et al.: Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1. Sci Rep, 5, S. 17369, 2015.
  • Cheng, Timothy H. T.; Thompson, Deborah J.; O'Mara, Tracy A.; Painter, Jodie N.; Glubb, Dylan M.; Flach, Susanne et al.: Five endometrial cancer risk loci identified through genome-wide association analysis. Nat Genet, 48 (6), S. 667–674, 2016.
  • Cheng, Fei; Twardowski, Laura; Reifenberg, Kurt; Winter, Kerstin; Canisius, Antje; Pross, Eva et al.: Combined B, T and NK Cell Deficiency Accelerates Atherosclerosis in BALB/c Mice. PLoS One, 11 (8), e0157311, 2016.
  • Cheng, Fei; Twardowski, Laura; Fehr, Sarah; Aner, Christoph; Schaeffeler, Elke; Joos, Thomas et al.: Selective p38alpha MAP kinase/MAPK14 inhibition in enzymatically-modified LDL-stimulated human monocytes: implications for atherosclerosis. FASEB J, 2016.
  • Cho, Doo-Yeoun; Shen, Joan H. Q.; Lemler, Suzanne M.; Skaar, Todd C.; Li, Lang; Blievernicht, Julia et al.: Rifampin enhances cytochrome P450 (CYP) 2B6-mediated efavirenz 8-hydroxylation in healthy volunteers. Drug Metab Pharmacokinet, 31 (2), S. 107–116, 2016.
  • Copsey, Bethan; Hopewell, Sally; Becker, Clemens; Cameron, Ian D.; Lamb, Sarah E.: Appraising the uptake and use of recommendations for a common outcome data set for clinical trials: a case study in fall injury prevention. Trials, 17 (1), S. 131, 2016.
  • Couch, Fergus J.; Kuchenbaecker, Karoline B.; Michailidou, Kyriaki; Mendoza-Fandino, Gustavo A.; Nord, Silje; Lilyquist, Janna et al.: Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer. Nat Commun, 7, S. 11375, 2016.
  • Crea, Filippo; Bairey Merz, C. Noel; Beltrame, John F.; Kaski, Juan Carlos; Ogawa, Hisao; Ong, Peter et al.: The parallel tales of microvascular angina and heart failure with preserved ejection fraction: a paradigm shift. Eur Heart J, 2016.
  • Dai, Beiying; Grau, Michael; Juilland, Melanie; Klener, Pavel; Horing, Elisabeth; Molinsky, Jan et al.: B-cell receptor driven MALT1 activity regulates MYC signaling in mantle cell lymphoma. Blood, 2016.
  • Darabi, Hatef; Beesley, Jonathan; Droit, Arnaud; Kar, Siddhartha; Nord, Silje; Moradi Marjaneh, Mahdi et al.: Fine scale mapping of the 17q22 breast cancer locus using dense SNPs, genotyped within the Collaborative Oncological Gene-Environment Study (COGs). Sci Rep, 6, S. 32512, 2016.
  • Darmani, Ghazaleh; Zipser, Carl M.; Böhmer, Gabriele M.; Deschet, Karine; Müller-Dahlhaus, Florian; Belardinelli, Paolo et al.: Effects of the Selective α5-GABAAR Antagonist S44819 on Excitability in the Human Brain. J. Neurosci., 36 (49), S. 12312–12320, 2016.
  • Dasgupta, Yashodhara; Koptyra, Mateusz; Hoser, Grazyna; Kantekure, Kanchan; Roy, Darshan; Gornicka, Barbara et al.: Normal ABL1 is a tumor suppressor and therapeutic target in human and mouse leukemias expressing oncogenic ABL1 kinases. Blood, 127 (17), S. 2131–2143, 2016.
  • Dropmann, Anne; Dediulia, Tatjana; Breitkopf-Heinlein, Katja; Korhonen, Hanna; Janicot, Michel; Weber, Susanne N. et al.: TGF-beta1 and TGF-beta2 abundance in liver diseases of mice and men. Oncotarget, 7 (15), S. 19499–19518, 2016.
  • Dunning, Alison M.; Michailidou, Kyriaki; Kuchenbaecker, Karoline B.; Thompson, Deborah; French, Juliet D.; Beesley, Jonathan et al.: Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170. Nat Genet, 48 (4), S. 374–386, 2016.
  • Easton, Douglas F.; Lesueur, Fabienne; Decker, Brennan; Michailidou, Kyriaki; Li, Jun; Allen, Jamie et al.: No evidence that protein truncating variants in BRIP1 are associated with breast cancer risk: implications for gene panel testing. J Med Genet, 53 (5), S. 298–309, 2016.
  • Emami, Riedmaier A.; Burk, O.; van Eijck, B. A.; Schaeffeler, E.; Klein, K.; Fehr, S. et al.: Variability in hepatic expression of organic anion transporter 7/SLC22A9, a novel pravastatin uptake transporter: impact of genetic and regulatory factors. In: Pharmacogenomics J 16 (4), S. 341–351, 2016.
  • Fisel, P.; Schaeffeler, E.; Schwab, M.: DNA Methylation of ADME Genes. Clin Pharmacol Ther, 99 (5), S. 512–527, 2016.
  • Florian, Anca; Rosch, Sabine; Bietenbeck, Michael; Engelen, Markus; Stypmann, Jorg; Waltenberger, Johannes et al.: Cardiac involvement in female Duchenne and Becker muscular dystrophy carriers in comparison to their first-degree male relatives: a comparative cardiovascular magnetic resonance study. Eur Heart J Cardiovasc Imaging, 17 (3), S. 326–333, 2016.
  • Fuerst, Daniel; Neuchel, Christine; Niederwieser, Dietger; Bunjes, Donald; Gramatzki, Martin; Wagner, Eva et al.: Matching for the MICA-129 polymorphism is beneficial in unrelated hematopoietic stem cell transplantation. Blood, 2016.
  • Ge RF, Falkenstern; M, Kimmich; M, Wohlleber: Crizotinib Induced Rapid Remissions of Lung Adenocarcinoma. Oncology and cancer case reports, 02 (02), 2016.
  • Ge RF, Falkenstern; M, Kimmich; M, Wohlleber: Occurrence of Metachronous Multiple Malignancies. Review of the Literature. Oncology and cancer case reports, 02 (02), 2016.
  • Ge RF, Falkenstern; M, Kimmich; M, Wohlleber: Pneumothorax Ex Vacuo by Severe pleuramesothelioma. Oncology and cancer case reports, 02 (02), 2016.
  • Ghallab, Ahmed; Celliere, Geraldine; Henkel, Sebastian G.; Driesch, Dominik; Hoehme, Stefan; Hofmann, Ute et al.: Model-guided identification of a therapeutic strategy to reduce hyperammonemia in liver diseases. J Hepatol, 64 (4), S. 860–871, 2016.
  • Ghoussaini, Maya; French, Juliet D.; Michailidou, Kyriaki; Nord, Silje; Beesley, Jonathan; Canisus, Sander et al.: Evidence that the 5p12 Variant rs10941679 Confers Susceptibility to Estrogen-Receptor-Positive Breast Cancer through FGF10 and MRPS30 Regulation. Am J Hum Genet, 99 (4), S. 903–911, 2016.
  • Godoy, Patricio; Widera, Agata; Schmidt-Heck, Wolfgang; Campos, Gisela; Meyer, Christoph; Cadenas, Cristina et al.: Gene network activity in cultivated primary hepatocytes is highly similar to diseased mammalian liver tissue. Arch Toxicol, 90 (10), S. 2513–2529, 2016.
  • Gori, Tommaso; Sechtem, Udo; Munzel, Thomas: Severe Prinzmetal-Type Coronary Artery Spasm Causing Recurrent ST-Segment Elevation and Reversible Obstruction of a Bioresorbable Scaffold. JACC Cardiovasc Interv, 9 (2), S. 195–197, 2016.
  • Graeter, T. P.; Friedel, G.: Pulmonale Metastasenchirurgie des kolorektalen Karzinoms. Zentralbl Chir, 141 (3), S. 341–354, 2016.
  • Greulich, Simon; Kindermann, Ingrid; Schumm, Julia; Perne, Andrea; Birkmeier, Stefan; Grun, Stefan et al.: Predictors of outcome in patients with parvovirus B19 positive endomyocardial biopsy. Clin Res Cardiol, 105 (1), S. 37–52, 2016.
  • Greulich, Simon; Kitterer, Daniel; Kurmann, Reto; Henes, Joerg; Latus, Joerg; Gloekler, Steffen et al.: Cardiac involvement in patients with rheumatic disorders: Data of the RHEU-M(A)R study. Int J Cardiol, 224, S. 37–49, 2016.
  • Greulich, Simon; Kitterer, Daniel; Latus, Joerg; Aguor, Eissa; Steubing, Hannah; Kaesemann, Philipp et al.: Comprehensive Cardiovascular Magnetic Resonance Assessment in Patients With Sarcoidosis and Preserved Left Ventricular Ejection Fraction. Circ Cardiovasc Imaging, 9 (11), 2016.
  • Greulich, Simon; Mahrholdt, Heiko: Prognosis of Myocardial Damage in Sarcoidosis Patients With Preserved Left Ventricular Ejection Fraction: Always Look at the Bright Side of Cardiovascular Magnetic Resonance. Circ Cardiovasc Imaging, 9 (1), e004417, 2016.
  • Guo, Yan; Warren Andersen, Shaneda; Shu, Xiao-Ou; Michailidou, Kyriaki; Bolla, Manjeet K.; Wang, Qin et al.: Genetically Predicted Body Mass Index and Breast Cancer Risk: Mendelian Randomization Analyses of Data from 145,000 Women of European Descent. PLoS Med, 13 (8), e1002105, 2016.
  • Hamdi, Yosr; Soucy, Penny; Adoue, Veronique; Michailidou, Kyriaki; Canisius, Sander; Lemacon, Audrey et al.: Association of breast cancer risk with genetic variants showing differential allelic expression: Identification of a novel breast cancer susceptibility locus at 4q21. Oncotarget, 2016.
  • Hansen, Matthias: Echokardiografie – Das Wichtigste zu TTE und TEE. Lege artis, 6 (02), S. 104–107, 2016.
  • Hendel, Robert C.; Friedrich, Matthias G.; Schulz-Menger, Jeanette; Zemmrich, Claudia; Bengel, Frank; Berman, Daniel S. et al.: CMR First-Pass Perfusion for Suspected Inducible Myocardial Ischemia. JACC Cardiovasc Imaging, 9 (11), S. 1338–1348, 2016.
  • Ho, Anthony D.; Schetelig, Johannes; Bochtler, Tilmann; Schaich, Markus; Schafer-Eckart, Kerstin; Hanel, Mathias et al.: Allogeneic Stem Cell Transplantation Improves Survival in Patients with Acute Myeloid Leukemia Characterized by a High Allelic Ratio of Mutant FLT3-ITD. Biol Blood Marrow Transplant, 22 (3), S. 462–469, 2016.
  • Hocher, B.; Haumann, H.; Rahnenfuhrer, J.; Reichetzeder, C.; Kalk, P.; Pfab, T. et al.: Maternal eNOS deficiency determines a fatty liver phenotype of the offspring in a sex dependent manner. In: Epigenetics. 11 (7), S. 539–552, 2016.
  • Hofmann, U.; Thiel, C.; Ghallab, A.; Gebhardt, R.; Hengstler, J. G.; Kuepfer, L.: Von der Maus zum Menschen (11), S. 28–31, 2016.
  • Hoppe, Reiner; Fan, Ping; Buttner, Florian; Winter, Stefan; Tyagi, Amit K.; Cunliffe, Heather et al.: Profiles of miRNAs matched to biology in aromatase inhibitor resistant breast cancer. Oncotarget, 2016.
  • Horne, Hisani N.; Chung, Charles C.; Zhang, Han; Yu, Kai; Prokunina-Olsson, Ludmila; Michailidou, Kyriaki et al.: Fine-Mapping of the 1p11.2 Breast Cancer Susceptibility Locus. PLoS One, 11 (8), e0160316, 2016.
  • Isselbacher, Eric M.; Bonaca, Marc P.; Di Eusanio, Marco; Froehlich, James; Bassone, Eduardo; Sechtem, Udo et al.: Recurrent Aortic Dissection: Observations From the International Registry of Aortic Dissection. Circulation, 134 (14), S. 1013–1024, 2016.
  • Jiang, Mengxi; Klein, Marcus; Zanger, Ulrich M.; Mohammad, Mohammad K.; Cave, Matthew C.; Gaikwad, Nilesh W. et al.: Inflammatory regulation of steroid sulfatase: A novel mechanism to control estrogen homeostasis and inflammation in chronic liver disease. J Hepatol, 64 (1), S. 44–52, 2016.
  • Jurinovic, Vindi; Kridel, Robert; Staiger, Annette M.; Szczepanowski, Monika; Horn, Heike; Dreyling, Martin H. et al.: Clinicogenetic risk models predict early progression of follicular lymphoma after first-line immunochemotherapy. Blood, 128 (8), S. 1112–1120, 2016.
  • Kalla, C.; Gruber, K.; Rosenwald, A.; Kimmich, M.; Kohlhäufl, M.; Friedel, G.; Ott, G.: ROS1 gene rearrangement and expression of splice isoforms in lung cancer, diagnosed by a novel quantitative RT-PCR assay. J Mod Hum Pathol., S. 25–34, 2016.
  • Kalman, L. V.; Agundez, J.; Appell, M. L.; Black, J. L.; Bell, G. C.; Boukouvala, S. et al.: Pharmacogenetic allele nomenclature: International workgroup recommendations for test result reporting. Clin Pharmacol Ther, 99 (2), S. 172–185, 2016.
  • Kandel, B. A.; Thomas, M.; Winter, S.; Damm, G.; Seehofer, D.; Burk, O. et al.: Genomewide comparison of the inducible transcriptomes of nuclear receptors CAR, PXR and PPARalpha in primary human hepatocytes. In: Biochim. Biophys. Acta 1859 (9), S. 1218–1227, 2016.
  • Kar, Siddhartha P.; Beesley, Jonathan; Amin Al Olama, Ali; Michailidou, Kyriaki; Tyrer, Jonathan; Kote-Jarai, Zsofia et al.: Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types. Cancer Discov, 6 (9), S. 1052–1067, 2016.
  • Keller, Roland; Klein, Marcus; Thomas, Maria; Drager, Andreas; Metzger, Ute; Templin, Markus F. et al.: Coordinating Role of RXRalpha in Downregulating Hepatic Detoxification during Inflammation Revealed by Fuzzy-Logic Modeling. PLoS Comput Biol, 12 (1), e1004431, 2016.
  • Kendrick, Samantha; Tus, Katalin; Wright, George; Jaffe, Elaine S.; Rosenwald, Andreas; Campo, Elias et al.: Diffuse large B-cell lymphoma cell-of-origin classification using the Lymph2Cx assay in the context of BCL2 and MYC expression status. Leuk Lymphoma, 57 (3), S. 717–720, 2016.
  • Kimmel, Martin; Shi, Jing; Latus, Joerg; Wasser, Christoph; Kitterer, Daniel; Braun, Niko; Alscher, Mark Dominik: Association of Renal Stress/Damage and Filtration Biomarkers with Subsequent AKI during Hospitalization among Patients Presenting to the Emergency Department. Clin J Am Soc Nephrol, 11 (6), S. 938–946, 2016.
  • Kimmel, Martin; Shi, Jing; Wasser, Christoph; Biegger, Dagmar; Alscher, Mark Dominik; Schanz, Moritz Bastian: Urinary TIMP-2.IGFBP7 - Novel Biomarkers to Predict Acute Kidney Injury. Am J Nephrol, 43 (5), S. 375–382, 2016.
  • Kitterer, Daniel; Braun, Niko; Alscher, M. Dominik; Segerer, Stephan; Latus, Joerg: The number of patients with severe encapsulating peritoneal sclerosis is decreasing in a large referral center in Germany. Int J Nephrol Renovasc Dis, 9, S. 183–186, 2016.
  • Kitterer, Daniel; Greulich, Simon; Grun, Stefan; Segerer, Stephan; Mustonen, Jukka; Alscher, M. Dominik et al.: Electrocardiographic abnormalities and relative bradycardia in patients with hantavirus-induced nephropathia epidemica. Eur J Intern Med, 33, S. 67–73, 2016.
  • Kitterer, Daniel; Segerer, Stephan; Dippon, Juergen; Alscher, M. Dominik; Braun, Niko; Latus, Joerg: Smoking Is a Risk Factor for Severe Acute Kidney Injury in Hantavirus-Induced Nephropathia Epidemica. Nephron, 134 (2), S. 89–94, 2016.
  • Klag, Thomas; Cantara, Giulio; Sechtem, Udo; Athanasiadis, Anastasios: Interleukin-6 Kinetics can be Useful for Early Treatment Monitoring of Severe Bacterial Sepsis and Septic Shock. Infect Dis Rep, 8 (1), S. 6213, 2016.
  • Klenk, Jochen; Schwickert, Lars; Palmerini, Luca; Mellone, Sabato; Bourke, Alan; Ihlen, Espen A. F. et al.: The FARSEEING real-world fall repository: a large-scale collaborative database to collect and share sensor signals from real-world falls. Eur Rev Aging Phys Act, 13, S. 8, 2016.
  • Klenk, Jochen; Srulijes, Karin; Schatton, Cornelia; Schwickert, Lars; Maetzler, Walter; Becker, Clemens; Synofzik, Matthis: Ambulatory Activity Components Deteriorate Differently across Neurodegenerative Diseases: A Cross-Sectional Sensor-Based Study. Neurodegener Dis, 16 (5-6), S. 317–323, 2016.
  • Koch, K.; Hoster, E.; Ziepert, M.; Unterhalt, M.; Ott, G.; Rosenwald, A. et al.: Clinical, pathological and genetic features of follicular lymphoma grade 3A: a joint analysis of the German low-grade and high-grade lymphoma study groups GLSG and DSHNHL. Ann Oncol, 27 (7), S. 1323–1329, 2016.
  • Kremsner, P. G.; Adegnika, A. A.; Hounkpatin, A. B.; Zinsou, J. F.; Taylor, T. E.; Chimalizeni, Y. et al.: Intramuscular Artesunate for Severe Malaria in African Children: A Multicenter Randomized Controlled Trial. PLoS Med, 13 (1), e1001938, 2016.
  • Kyriss, T.; Lenz, U.; Friedel, G.: Rippenosteosynthesen – funktionsverbessernd? Zentralbl Chir, 141 (S 01), S6-S11, 2016.
  • Lawrenson, Kate; Kar, Siddhartha; McCue, Karen; Kuchenbaeker, Karoline; Michailidou, Kyriaki; Tyrer, Jonathan et al.: Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus. Nat Commun, 7, S. 12675, 2016.
  • Lei, Jieping; Rudolph, Anja; Moysich, Kirsten B.; Behrens, Sabine; Goode, Ellen L.; Bolla, Manjeet K. et al.: Genetic variation in the immunosuppression pathway genes and breast cancer susceptibility: a pooled analysis of 42,510 cases and 40,577 controls from the Breast Cancer Association Consortium. Hum Genet, 135 (1), S. 137–154, 2016.
  • Leich, E.; Hoster, E.; Wartenberg, M.; Unterhalt, M.; Siebert, R.; Koch, K. et al.: Similar clinical features in follicular lymphomas with and without breaks in the BCL2 locus. Leukemia, 30 (4), S. 854–860, 2016.
  • Leuthold, Patrick; Schaeffeler, Elke; Winter, Stefan; Buttner, Florian; Hofmann, Ute; Murdter, Thomas E. et al.: Comprehensive metabolomic and lipidomic profiling of human kidney tissue: a platform comparison. J Proteome Res, 2016.
  • Lim, J. S.; Sutiman, N.; Muerdter, T. E.; Singh, O.; Cheung, Y. B.; Ng, R. C. et al.: Association of CYP2C19*2 and associated haplotypes with lower norendoxifen concentrations in tamoxifen-treated Asian breast cancer patients. Br J Clin Pharmacol, 81 (6), S. 1142–1152, 2016.
  • Lindemann, Ulrich; Beck, Luisa; Becker, Clemens: Effect of course length and corridor width on the 2-minute walk test performance in geriatric patients. Clin Rehabil, 2016.
  • Lindemann, Ulrich; Klenk, Jochen; Becker, Clemens: Assessment of fatigability of older women during sit-to-stand performance. Aging Clin Exp Res, 28 (5), S. 889–893, 2016.
  • Lindemann, Ulrich; Mohr, Christian; Machann, Juergen; Blatzonis, Konstantinos; Rapp, Kilian; Becker, Clemens: Association between Thigh Muscle Volume and Leg Muscle Power in Older Women. PLoS One, 11 (6), e0157885, 2016.
  • Lindemann, Ulrich; Schwenk, Michael; Schmitt, Syn; Weyrich, Michael; Schlicht, Wolfgang; Becker, Clemens: Effekt von Bergauf- und Bergabgehen auf die Gehfahigkeit geriatrischer Patienten mit Rollator. Z Gerontol Geriatr, 2016.
  • Lindemann, Ulrich; Schwenk, Michael; Klenk, Jochen; Kessler, Max; Weyrich, Michael; Kurz, Franziska; Becker, Clemens: Problems of older persons using a wheeled walker. Aging Clin Exp Res, 28 (2), S. 215–220, 2016.
  • Liu, Jingjing; Loncar, Ivona; Collee, J. Margriet; Bolla, Manjeet K.; Dennis, Joe; Michailidou, Kyriaki et al.: rs2735383, located at a microRNA binding site in the 3'UTR of NBS1, is not associated with breast cancer risk. Sci Rep, 6, S. 36874, 2016.
  • Luckert, Claudia; Schulz, Christina; Lehmann, Nadja; Thomas, Maria; Hofmann, Ute; Hammad, Seddik et al.: Comparative analysis of 3D culture methods on human HepG2 cells. Arch Toxicol, 2016.
  • Lyon, Alexander R.; Bossone, Eduardo; Schneider, Birke; Sechtem, Udo; Citro, Rodolfo; Underwood, S. Richard et al.: Current state of knowledge on Takotsubo syndrome: a Position Statement from the Taskforce on Takotsubo Syndrome of the Heart Failure Association of the European Society of Cardiology. Eur J Heart Fail, 18 (1), S. 8–27, 2016.
  • Machowska, Anna; Alscher, Mark Dominik; Reddy Vanga, Satyanarayana; Koch, Michael; Aarup, Michael; Qureshi, Abdul Rashid et al.: Factors influencing access to education, decision making, and receipt of preferred dialysis modality in unplanned dialysis start patients. Patient Prefer Adherence, 10, S. 2229–2237, 2016.
  • Mahrholdt, Heiko; Sechtem, Udo: Bildgebende Verfahren bei Myokarditis und Kardiomyopathie. Dtsch Med Wochenschr, 141 (2), S. 89–94, 2016.
  • Mansouri, Larry; Noerenberg, Daniel; Young, Emma; Mylonas, Elena; Abdulla, Maysaa; Frick, Mareike et al.: Frequent NFKBIE deletions are associated with poor outcome in primary mediastinal B-cell lymphoma. Blood, 128 (23), S. 2666–2670, 2016.
  • Martin, J. H.; Henry, D.; Gray, J.; Day, R.; Bochner, F.; Ferro, A. et al.: Achieving the World Health Organization's vision for clinical pharmacology. Br J Clin Pharmacol, 81 (2), S. 223–227, 2016.
  • Matthaei, J.; Tzvetkov, M. V.; Strube, J.; Sehrt, D.; Sachse-Seeboth, C.; Hjelmborg, J. B. et al.: Heritability of Caffeine Metabolism: Environmental Effects Masking Genetic Effects on CYP1A2 Activity but Not on NAT2. In: Clin Pharmacol Ther 100 (6), S. 606–616, 2016.
  • Matthaei, J.; Tzvetkov, M. V.; Gal, V.; Sachse-Seeboth, C.; Sehrt, D.; Hjelmborg, J. B. et al.: Low heritability in pharmacokinetics of talinolol: a pharmacogenetic twin study on the heritability of the pharmacokinetics of talinolol, a putative probe drug of MDR1 and other membrane transporters. In: Genome Med 8 (1), S. 119, 2016.
  • Mayr, Agnes; Kitterer, Daniel; Latus, Joerg; Steubing, Hannah; Henes, Joerg; Vecchio, Francesco et al.: Evaluation of myocardial involvement in patients with connective tissue disorders: a multi-parametric cardiovascular magnetic resonance study. J Cardiovasc Magn Reson, 18 (1), S. 67, 2016.
  • Meeks, Huong D.; Song, Honglin; Michailidou, Kyriaki; Bolla, Manjeet K.; Dennis, Joe; Wang, Qin et al.: BRCA2 Polymorphic Stop Codon K3326X and the Risk of Breast, Prostate, and Ovarian Cancers. J Natl Cancer Inst, 108 (2), 2016.
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  • Roffi, Marco; Patrono, Carlo; Collet, Jean-Philippe; Mueller, Christian; Valgimigli, Marco; Andreotti, Felicita et al.: 2015 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: Task Force for the Management of Acute Coronary Syndromes in Patients Presenting without Persistent ST-Segment Elevation of the European Society of Cardiology (ESC). Eur Heart J, 37 (3), S. 267–315, 2016.
  • Schneider, Birke; Sechtem, Udo: Influence of Age and Gender in Takotsubo Syndrome. Heart Fail Clin, 12 (4), S. 521–530, 2016.
  • Schwab, M.; Billing, H.; Mörike, K.: Drug Use, Dosing, and Toxicity in Renal Disease. In: Denis F. Geary and Franz Schaefer (eds.). In: Pediatric Kidney Disease.2nd edition, Chapter 70 in Section 14: Nephrotoxicity and Pharmacotherapy.Springer Science + Business Media, 2016.
  • Sechtem, U.; Greulich, S.; Ong, P.: Empfehlungen der ESC-Leitlinien zur kardiovaskularen Bildgebung. Herz, 41 (5), S. 362–370, 2016.
  • Sechtem, Udo; Mahrholdt, Heiko; Ong, Peter; Athanasiadis, Anastasios; Schaufele, Tim: Testing in Patients With Stable Coronary Artery Disease- The Debate Continues. Circ J, 80 (4), S. 802–810, 2016.
  • Swerdlow, Steven H.; Kuzu, Isinsu; Dogan, Ahmet; Dirnhofer, Stephan; Chan, John K. C.; Sander, Birgitta et al.: The many faces of small B cell lymphomas with plasmacytic differentiation and the contribution of MYD88 testing. Virchows Arch, 468 (3), S. 259–275, 2016.
  • van der Wouden, C. H.; Swen, J. J.; Samwald, M.; Mitropoulou, C.; Schwab, M.; Guchelaar, H. J.: A brighter future for the implementation of pharmacogenomic testing. In: Eur J Hum Genet 24 (12), S. 1658–1660, 2016.
  • Vohringer, Matthias: Die Knochenmarkpunktion. Dtsch Med Wochenschr, 141 (6), S. 410–413, 2016.
  • Vrints, Christiaan J. M.; Senior, Roxy; Crea, Filippo; Sechtem, Udo: Assessing suspected angina: requiem for coronary computed tomography angiography or exercise electrocardiogram? Eur Heart J, 2016.
  • Weiß, H.: Impasse and understanding in the analysis of a severely traumatized patient, In: Lang, H., Dybel, P., Pagel, G. (Eds.). In: Hermeneutik und Psychoanalyse. Perspektiven und Kontroversen. Würzburg: Königshausen & Neumann, S. 307–322, 2016.
  • Weiß, H.: Konzeptionelle Überlegungen zum Verhältnis von empirischer und klinischer psychoanalytischer Forschung am Beispiel chronischer Depressivität, In: Böker, H., Hartwich, P., Northoff, G. (Eds.). In: Neuro-psychodynamische Psychiatrie. Berlin, Heidelberg: Springer, S. 525–529, 2016.
  • Weiß, H.; Schött, M.: Psychoanalytische Psychotherapie im teilstationären Setting, In: Böker, H., Hartwich, P., Northoff, G. (Eds.). In: Neuro-psychodynamische Psychiatrie. Berlin, Heidelberg: Springer, S. 437–451, 2016.
  • Xerri, Luc; Dirnhofer, Stephan; Quintanilla-Martinez, Leticia; Sander, Birgitta; Chan, John K. C.; Campo, Elias et al.: The heterogeneity of follicular lymphomas: from early development to transformation. Virchows Arch, 468 (2), S. 127–139, 2016.
  • Auffray, C.; Caulfield, T.; Griffin, J. L.; Khoury, M. J.; Lupski, J. R.; Schwab, M.: From genomic medicine to precision medicine: highlights of 2015. Genome Med, 8 (1), S. 12, 2016.
  • Cascorbi, I.; Schwab, M.: Epigenetics in Drug Response. Clin Pharmacol Ther, 99 (5), S. 468–470, 2016.
  • Danesi, R.; Del, Re M.; Ciccolini, J.; Schellens, J. H.; Schwab, M.; van Schaik, R. H.; van Kuilenburg, A. B.: Prevention of fluoropyrimidine toxicity: do we still have to try our patient's luck? In: Ann Oncol, 2016.
  • Greulich, Simon; Mahrholdt, Heiko: Prognosis of Myocardial Damage in Sarcoidosis Patients With Preserved Left Ventricular Ejection Fraction: Always Look at the Bright Side of Cardiovascular Magnetic Resonance. Circ Cardiovasc Imaging, 9 (1), e004417, 2016.
  • Ong, Peter; Sechtem, Udo: Controversies in the treatment of patients with STEMI and multivessel disease: is it time for PCI of all lesions? Clin Res Cardiol, 105 (6), S. 467–470, 2016.
  • Sechtem, Udo: Angina pectoris. Dtsch med Wochenschr, 141 (04), S. 240–241, 2016.
  • Sechtem, Udo: Aortenklappenersatz: Gute Ergebnisse fur Katheterklappe auch bei mittlerem Risiko. Dtsch Med Wochenschr, 141 (13), S. 923, 2016.
Habilitations
  • Ong, Peter
    Koronare Vasomotionsstörungen bei Patienten mit Angina pectoris und nicht-stenosierten Koronararterien, Universität Tübingen
  • Braun, Niko
    Ernennung zum außerplanmäßigen Professor, Universität Tübingen

PHD/MD Theses


  • Hirobe-Jahn, Satoko
    Assoziation von FXR- und SR-BI- Genvarianten mit der Gallensteinerkrankung, Universität Hohenheim
  • Morár, Natalie
    5-Jahres Prognose bezüglich Lebensqualität und Koronarereignissen bei Patienten mit stabiler Angina Pectoris und nicht-stonosierten Koronararterien (ACOVA-Follow-Up-Studie), Universität Tübingen
  • Staiger, Annette
    Genexpressionsprofile follikulärer Lymphome und ihre prognostische Relevanz. Universität Stuttgart
  • Tremmel, Roman
    Bioinformatische Analyse und Funktionelle Charakterisierung von Strukturellen Genvarianten in ADME-Genen in Humaner Leber, Universität Hohenheim


Master Theses


  • Kugler, Nicole (geb. Knapp)
    Role of microRNAs for drug metabolism during inflammation, Universität Tübingen
  • Kleih, Markus
    GST-π als potentielles Target zur Behandlung des Mantelzelllymphoms, Universität Stuttgart


Bachelor


  • Kalmbach, Sabrina
    Etabilierung eines FISH-basierten Diagnostikverfahrens zur Detektion von 11q-Aberrationen bei Burkitt Lymphomen ohne MYC-Translokation, Hochschule Furtwangen