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Publications 2012 (IKP + RBK)

  • Aikpokpo, N., Hill, S., and Sechtem, U. Case report: acute coronary artery spasm in a patient in the setting of non-cardiac surgery. Clin Res Cardiol. 101:683-686, 2012
  • Alscher, M. D. and Sechtem, U. [Cardiorenal syndrome]. Internist (Berl) 53:309-317, 2012
  • Arlanov, R., Porter, A., Strand, D., Brough, R., Karpova, D., Kerb, R., Wojnowski, L., Schwab, M., and Lang, T. Functional characterization of protein variants of the human multidrug transporter ABCC2 by a novel targeted expression system in fibrosarcoma cells. Hum Mutat 33:750-762, 2012
  • Athanasiadis, A. and Sechtem, U. [Update coronary artery disease: important progresses in acute and chronic therapy]. MMW.Fortschr.Med 154:58-60, 22-3-2012
  • Bagala, F., Becker, C., Cappello, A., Chiari, L., Aminian, K., Hausdorff, J. M., Zijlstra, W., and Klenk, J. Evaluation of accelerometer-based fall detection algorithms on real-world falls. PLoS One 7:e37062, 2012
  • Baselga, J., Cortes, J., Kim, S. B., Im, S. A., Hegg, R., Im, Y. H., Roman, L., Pedrini, J. L., Pienkowski, T., Knott, A., Clark, E., Benyunes, M. C., Ross, G., and Swain, S. M. Pertuzumab plus trastuzumab plus docetaxel for metastatic breast cancer. N Engl J Med 366:109-119, 12-1-2012 AG Aulitzky: Beteiligung an Klinischen Studien
  • Becker, C., Schwickert, L., Mellone, S., Bagala, F., Chiari, L., Helbostad, J. L., Zijlstra, W., Aminian, K., Bourke, A., Todd, C., Bandinelli, S., Kerse, N., and Klenk, J. Proposal for a multiphase fall model based on real-world fall recordings with body-fixed sensors. Z Gerontol Geriatr 45:707-715, 2012
  • Bleibler, F., Konnopka, A., Benzinger, P., Rapp, K., and Konig, H. H. The health burden and costs of incident fractures attributable to osteoporosis from 2010 to 2050 in Germany-a demographic simulation model. Osteoporos Int, 14-7-2012 Epub
  • Brandstetter, S., Klenk, J., Berg, S., Galm, C., Fritz, M., Peter, R., Prokopchuk, D., Steiner, R. P., Wartha, O., Steinacker, J., and Wabitsch, M. Overweight prevention implemented by primary school teachers: a randomised controlled trial. Obes facts 5:1-11, 2012
  • Braun, N., Fritz, P., Ulmer, C., Latus, J., Kimmel, M., Biegger, D., Ott, G., Reimold, F., Thon, K. P., Dippon, J., Segerer, S., and Alscher, M. D. Histological criteria for encapsulating peritoneal sclerosis - a standardized approach. PLoS One 7:e48647, 2012
  • Burk, O., Piedade, R., Ghebreghiorghis, L., Fait, J., Nussler, A., Gil, J., Windshugel, B., and Schwab, M. Differential effects of clinically used derivatives and metabolites of artemisinin in the activation of constitutive androstane receptor isoforms. Br J Pharmacol 167:666-681, 2012
  • Camm, A. J., Lip, G. Y., De, Caterina R., Savelieva, I., Atar, D., Hohnloser, S. H., Hindricks, G., Kirchhof, P., Bax, J. J., Baumgartner, H., Ceconi, C., Dean, V., Deaton, C., Fagard, R., Funck-Brentano, C., Hasdai, D., Hoes, A., Kirchhof, P., Knuuti, J., Kolh, P., McDonagh, T., Moulin, C., Popescu, B. A., Reiner, Z., Sechtem, U., Sirnes, P. A., Tendera, M., Torbicki, A., Vahanian, A., Windecker, S., Vardas, P., Al-Attar, N., Alfieri, O., Angelini, A., Blomstrom-Lundqvist, C., Colonna, P., De, Sutter J., Ernst, S., Goette, A., Gorenek, B., Hatala, R., Heidbuchel, H., Heldal, M., Kristensen, S. D., Kolh, P., Le Heuzey, J. Y., Mavrakis, H., Mont, L., Filardi, P. P., Ponikowski, P., Prendergast, B., Rutten, F. H., Schotten, U., Van, Gelder, I, and Verheugt, F. W. 2012 focused update of the ESC Guidelines for the management of atrial fibrillation: An update of the 2010 ESC Guidelines for the management of atrial fibrillation * Developed with the special contribution of the European Heart Rhythm Association. Eur Heart J 33:2719-2747, 2012
  • Chu, H., Pazgier, M., Jung, G., Nuccio, S. P., Castillo, P. A., de Jong, M. F., Winter, M. G., Winter, S. E., Wehkamp, J., Shen, B., Salzman, N. H., Underwood, M. A., Tsolis, R. M., Young, G. M., Lu, W., Lehrer, R. I., Baumler, A. J., and Bevins, C. L. Human alpha-defensin 6 promotes mucosal innate immunity through self-assembled peptide nanonets. Science 337:477-481, 27-7-2012
  • Crane, A. L., Klein, K., Zanger, U. M., and Olson, J. R. Effect of CYP2B6*6 and CYP2C19*2 genotype on chlorpyrifos metabolism. Toxicology 293:115-122, 11-3-2012
  • Crane, A. L., Klein, K., and Olson, J. R. Bioactivation of chlorpyrifos by CYP2B6 variants. Xenobiotica 42:1255-1262, 10-7-2012
  • Dansin, E., Cinieri, S., Garrido, P., Griesinger, F., Isla, D., Koehler, M., and Kohlhaeufl, M. MO19390 (SAiL): bleeding events in a phase IV study of first-line bevacizumab with chemotherapy in patients with advanced non-squamous NSCLC. Lung Cancer 76:373-379, 2012
  • Dasari, P., Heber, S. D., Beisele, M., Torzewski, M., Reifenberg, K., Orning, C., Fries, A., Zapf, A. L., Baumeister, S., Lingelbach, K., Udomsangpetch, R., Bhakdi, S. C., Reiss, K., and Bhakdi, S. Digestive vacuole of Plasmodium falciparum released during erythrocyte rupture dually activates complement and coagulation. Blood 119:4301-4310, 3-5-2012
  • Deffenbacher, K. E., Iqbal, J., Sanger, W., Shen, Y., Lachel, C., Liu, Z., Liu, Y., Lim, M. S., Perkins, S. L., Fu, K., Smith, L., Lynch, J., Staudt, L. M., Rimsza, L. M., Jaffe, E., Rosenwald, A., Ott, G. K., Delabie, J., Campo, E., Gascoyne, R. D., Cairo, M. S., Weisenburger, D. D., Greiner, T. C., Gross, T. G., and Chan, W. C. Molecular distinctions between pediatric and adult mature B-cell non-Hodgkin lymphomas identified through genomic profiling. Blood 119:3757-3766, 19-4-2012
  • Dong, M., Murdter, T. E., Philippi, C., Loretz, B., Schaefer, U. F., Lehr, C. M., Schwab, M., and mmon-Treiber, S. Pulmonary delivery and tissue distribution of aerosolized antisense 2'-O-Methyl RNA containing nanoplexes in the isolated perfused and ventilated rat lung. Eur J Pharm Biopharm 81:478-485, 2012
  • Dreger, P., Dohner, H., McClanahan, F., Busch, R., Ritgen, M., Greinix, H., Fink, A. M., Knauf, W., Stadler, M., Pfreundschuh, M., Duhrsen, U., Brittinger, G., Hensel, M., Schetelig, J., Winkler, D., Buhler, A., Kneba, M., Schmitz, N., Hallek, M., and Stilgenbauer, S. Early autologous stem cell transplantation for chronic lymphocytic leukemia: long-term follow-up of the German CLL Study Group CLL3 trial. Blood 119:4851-4859, 24-5-2012 AG Aulitzky: Beteiligung an Klinischen Studien
  • Escher, M., Kainikkara, T. M., Grabner, A., Ott, G., Stange, E. F., and Herrlinger, K. R. [Histoplasmosis: uncommon opportunistic infection in a patient with HIV infection]. Deut Med Wochenschr 137:260-264, 2012
  • Falkenstern-Ge RF, Wohlleber M, Kimmich M, Bode-Erdmann S, Ott G, Kohlhäufl M. Late lung metastasis of primary endometrial cancer. Two rare cases of patients with late lung metastasis of primary endometrial cancer 14 and 17 years after initial treatment. memo 5:262-265, 2012
  • Falkenstern-Ge RF, Kimmich M, Friedel G, Tannapfel A, Neumann V, Kohlhäufl M. Diffuse idiopathische pulmonale neuroendokrine Zellhyperplasie: 7-jähriger Verlauf eines seltenen klinischen Syndroms. Pneumologie 66-P89, 2012
  • Fischer-Frohlich, C. L., Konigsrainer, A., Schaffer, R., Schaub, F., Pratschke, J., Pascher, A., Steurer, W., and Nadalin, S. Organ donation: when should we consider intestinal donation. Transpl.Int 25:1229-1240, 2012
  • Frank, C, O'Shaughnessy, E, and Weiß, H. Zum Verständnis klinischer Sackgassensituationen aus heutiger Sicht. Psyche Z Psychoanal 66:545-562, 2012
  • Friedrich, C., Ulmer, C., Rieber, F., Kern, E., Kohler, A., Schymik, K., Thon, K. P., and Lamade, W. Safety analysis of vagal nerve stimulation for continuous nerve monitoring during thyroid surgery. Laryngoscope 122:1979-1987, 2012
  • Fritz, P., Coy, J. F., Murdter, T. E., Ott, G., Alscher, M. D., and Friedel, G. TKTL-1 expression in lung cancer. Pathol Res Pract 208:203-209, 15-4-2012
  • Geissler A and Hollmann J. Stressoren am Arbeitsplatz - macht die Klinik Ärzte krank? Der Diabetologe 5:360-362, 2012
  • Geissler A and Hollmann J. Macht die Klinik Ärzte krank? Stressoren am Arbeitsplatz Klinik erkennen und Handlungsspielräume nutzen. Z Herz- Thorax- Gefäßchir 26:129-132, 2012
  • Gerlach, M., Maetzler, W., Broich, K., Hampel, H., Rems, L., Reum, T., Riederer, P., Stoffler, A., Streffer, J., and Berg, D. Biomarker candidates of neurodegeneration in Parkinson's disease for the evaluation of disease-modifying therapeutics. J Neural Transm. 119:39-52, 2012
  • Gersemann, M., Becker, S., Nuding, S., Antoni, L., Ott, G., Fritz, P., Oue, N., Yasui, W., Wehkamp, J., and Stange, E. F. Olfactomedin-4 is a glycoprotein secreted into mucus in active IBD. J Crohns Colitis 6:425-434, 2012
  • Ghoussaini, M., Fletcher, O., Michailidou, K., Turnbull, C., Schmidt, M. K., Dicks, E., Dennis, J., Wang, Q., Humphreys, M. K., Luccarini, C., Baynes, C., Conroy, D., Maranian, M., Ahmed, S., Driver, K., Johnson, N., Orr, N., Dos, Santos Silva, I, Waisfisz, Q., Meijers-Heijboer, H., Uitterlinden, A. G., Rivadeneira, F., Hall, P., Czene, K., Irwanto, A., Liu, J., Nevanlinna, H., Aittomaki, K., Blomqvist, C., Meindl, A., Schmutzler, R. K., Muller-Myhsok, B., Lichtner, P., Chang-Claude, J., Hein, R., Nickels, S., Flesch-Janys, D., Tsimiklis, H., Makalic, E., Schmidt, D., Bui, M., Hopper, J. L., Apicella, C., Park, D. J., Southey, M., Hunter, D. J., Chanock, S. J., Broeks, A., Verhoef, S., Hogervorst, F. B., Fasching, P. A., Lux, M. P., Beckmann, M. W., Ekici, A. B., Sawyer, E., Tomlinson, I., Kerin, M., Marme, F., Schneeweiss, A., Sohn, C., Burwinkel, B., Guenel, P., Truong, T., Cordina-Duverger, E., Menegaux, F., Bojesen, S. E., Nordestgaard, B. G., Nielsen, S. F., Flyger, H., Milne, R. L., Alonso, M. R., Gonzalez-Neira, A., Benitez, J., nton-Culver, H., Ziogas, A., Bernstein, L., Dur, C. C., Brenner, H., Muller, H., Arndt, V., Stegmaier, C., Justenhoven, C., Brauch, H., Bruning, T., Wang-Gohrke, S., Eilber, U., Dork, T., Schurmann, P., Bremer, M., Hillemanns, P., Bogdanova, N. V., Antonenkova, N. N., Rogov, Y. I., Karstens, J. H., Bermisheva, M., Prokofieva, D., Khusnutdinova, E., Lindblom, A., Margolin, S., Mannermaa, A., Kataja, V., Kosma, V. M., Hartikainen, J. M., Lambrechts, D., Yesilyurt, B. T., Floris, G., Leunen, K., Manoukian, S., Bonanni, B., Fortuzzi, S., Peterlongo, P., Couch, F. J., Wang, X., Stevens, K., Lee, A., Giles, G. G., Baglietto, L., Severi, G., McLean, C., Alnaes, G. G., Kristensen, V., Borrensen-Dale, A. L., John, E. M., Miron, A., Winqvist, R., Pylkas, K., Jukkola-Vuorinen, A., Kauppila, S., Andrulis, I. L., Glendon, G., Mulligan, A. M., Devilee, P., van Asperen, C. J., Tollenaar, R. A., Seynaeve, C., Figueroa, J. D., Garcia-Closas, M., Brinton, L., Lissowska, J., Hooning, M. J., Hollestelle, A., Oldenburg, R. A., van den Ouweland, A. M., Cox, A., Reed, M. W., Shah, M., Jakubowska, A., Lubinski, J., Jaworska, K., Durda, K., Jones, M., Schoemaker, M., Ashworth, A., Swerdlow, A., Beesley, J., Chen, X., Muir, K. R., Lophatananon, A., Rattanamongkongul, S., Chaiwerawattana, A., Kang, D., Yoo, K. Y., Noh, D. Y., Shen, C. Y., Yu, J. C., Wu, P. E., Hsiung, C. N., Perkins, A., Swann, R., Velentzis, L., Eccles, D. M., Tapper, W. J., Gerty, S. M., Graham, N. J., Ponder, B. A., Chenevix-Trench, G., Pharoah, P. D., Lathrop, M., Dunning, A. M., Rahman, N., Peto, J., and Easton, D. F. Genome-wide association analysis identifies three new breast cancer susceptibility loci. Nat Genet 44:312-318, 2012
  • Globas, C., Becker, C., Cerny, J., Lam, J. M., Lindemann, U., Forrester, L. W., Macko, R. F., and Luft, A. R. Chronic stroke survivors benefit from high-intensity aerobic treadmill exercise: a randomized control trial. Neurorehabil.Neural Repair 26:85-95, 2012
  • Gokbuget, N., Stanze, D., Beck, J., Diedrich, H., Horst, H. A., Huttmann, A., Kobbe, G., Kreuzer, K. A., Leimer, L., Reichle, A., Schaich, M., Schwartz, S., Serve, H., Starck, M., Stelljes, M., Stuhlmann, R., Viardot, A., Wendelin, K., Freund, M., and Hoelzer, D. Outcome of relapsed adult lymphoblastic leukemia depends on response to salvage chemotherapy, prognostic factors, and performance of stem cell transplantation. Blood 120:2032-2041, 6-9-2012 AG Aulitzky: Beteiligung an Klinischen Studien
  • Greulich, S., Bruder, O., Parker, M., Schumm, J., Grun, S., Schneider, S., Klem, I., Sechtem, U., and Mahrholdt, H. Comparison of exercise electrocardiography and stress perfusion CMR for the detection of coronary artery disease in women. J Cardiovasc Magn Reson. 14:36, 2012
  • Greulich, S., Schumm, J., Grun, S., Bruder, O., Sechtem, U., and Mahrholdt, H. Incremental value of late gadolinium enhancement for management of patients with hypertrophic cardiomyopathy. Am J Cardiol. 110:1207-1212, 15-10-2012
  • Grun, S., Backes, M., Schumm, J., Greulich, S., Ong, P., Geissler, A., Sechtem, U., and Mahrholdt, H. Long-term impact of undetected Kawasaki syndrome on coronary morphology and physiology. Circulation 125:e640-e644, 8-5-2012
  • Grun, S., Schumm, J., Greulich, S., Wagner, A., Schneider, S., Bruder, O., Kispert, E. M., Hill, S., Ong, P., Klingel, K., Kandolf, R., Sechtem, U., and Mahrholdt, H. Long-term follow-up of biopsy-proven viral myocarditis: predictors of mortality and incomplete recovery. J Am Coll.Cardiol. 59:1604-1615, 1-5-2012
  • Guillem, J. G., Ruby, J. A., Leibold, T., Akhurst, T. J., Yeung, H. W., Gollub, M. J., Ginsberg, M. S., Shia, J., Suriawinata, A. A., Riedel, E. R., Mazumdar, M., Saltz, L. B., Minsky, B. D., Nash, G. M., Paty, P. B., Temple, L. K., Weiser, M. R., and Larson, S. M. Neither FDG-PET Nor CT Is Able to Distinguish Between a Pathological Complete Response and an Incomplete Response After Neoadjuvant Chemoradiation in Locally Advanced Rectal Cancer: A Prospective Study. Ann Surg, 26-11-2012 Epub
  • Hamm, C. W., Bassand, J. P., Agewall, S., Bax, J., Boersma, E., Bueno, H., Caso, P., Dudek, D., Gielen, S., Huber, K., Ohman, M., Petrie, M. C., Sonntag, F., Uva, M. S., Storey, R. F., Wijns, W., and Zahger, D. [ESC guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation. The Task Force for the management of acute coronary syndromes (ACS) in patients presenting without persistent ST-segment elevation of the European Society of Cardiology (ESC)]. G.Ital.Cardiol.(Rome) 13:171-228, 2012
  • Hartmann, E. M., Bea, S., Navarro, A., Trapp, V., Campo, E., Ott, G., and Rosenwald, A. Increased tumor cell proliferation in mantle cell lymphoma is associated with elevated insulin-like growth factor 2 mRNA-binding protein 3 expression. Mod.Pathol 25:1227-1235, 2012
  • Hauser, I. A., Kruck, S., Gauer, S., Nies, A. T., Winter, S., Bedke, J., Geiger, H., Hoefeld, H., Kleemann, J., Asbe-Vollkopf, A., Engel, J., Burk, O., Schwab, M., and Schaeffeler, E. Human pregnane x receptor genotype of the donor but not of the recipient is a risk factor for delayed graft function after renal transplantation. Clin Pharmacol Ther 91:905-916, 2012
  • Hein, R., Maranian, M., Hopper, J. L., Kapuscinski, M. K., Southey, M. C., Park, D. J., Schmidt, M. K., Broeks, A., Hogervorst, F. B., Bueno-de-Mesquit, H. B., Muir, K. R., Lophatananon, A., Rattanamongkongul, S., Puttawibul, P., Fasching, P. A., Hein, A., Ekici, A. B., Beckmann, M. W., Fletcher, O., Johnson, N., Dos, Santos Silva, I, Peto, J., Sawyer, E., Tomlinson, I., Kerin, M., Miller, N., Marmee, F., Schneeweiss, A., Sohn, C., Burwinkel, B., Guenel, P., Cordina-Duverger, E., Menegaux, F., Truong, T., Bojesen, S. E., Nordestgaard, B. G., Flyger, H., Milne, R. L., Perez, J. I., Zamora, M. P., Benitez, J., nton-Culver, H., Ziogas, A., Bernstein, L., Clarke, C. A., Brenner, H., Muller, H., Arndt, V., Stegmaier, C., Rahman, N., Seal, S., Turnbull, C., Renwick, A., Meindl, A., Schott, S., Bartram, C. R., Schmutzler, R. K., Brauch, H., Hamann, U., Ko, Y. D., Wang-Gohrke, S., Dork, T., Schurmann, P., Karstens, J. H., Hillemanns, P., Nevanlinna, H., Heikkinen, T., Aittomaki, K., Blomqvist, C., Bogdanova, N. V., Zalutsky, I. V., Antonenkova, N. N., Bermisheva, M., Prokovieva, D., Farahtdinova, A., Khusnutdinova, E., Lindblom, A., Margolin, S., Mannermaa, A., Kataja, V., Kosma, V. M., Hartikainen, J., Chen, X., Beesley, J., Investigators, K., Lambrechts, D., Zhao, H., Neven, P., Wildiers, H., Nickels, S., Flesch-Janys, D., Radice, P., Peterlongo, P., Manoukian, S., Barile, M., Couch, F. J., Olson, J. E., Wang, X., Fredericksen, Z., Giles, G. G., Baglietto, L., McLean, C. A., Severi, G., Offit, K., Robson, M., Gaudet, M. M., Vijai, J., Alnaes, G. G., Kristensen, V., Borresen-Dale, A. L., John, E. M., Miron, A., Winqvist, R., Pylkas, K., Jukkola-Vuorinen, A., Grip, M., Andrulis, I. L., Knight, J. A., Glendon, G., Mulligan, A. M., Figueroa, J. D., Garcia-Closas, M., Lissowska, J., Sherman, M. E., Hooning, M., Martens, J. W., Seynaeve, C., Collee, M., Hall, P., Humpreys, K., Czene, K., Liu, J., Cox, A., Brock, I. W., Cross, S. S., Reed, M. W., Ahmed, S., Ghoussaini, M., Pharoah, P. D., Kang, D., Yoo, K. Y., Noh, D. Y., Jakubowska, A., Jaworska, K., Durda, K., Zlowocka, E., Sangrajrang, S., Gaborieau, V., Brennan, P., McKay, J., Shen, C. Y., Yu, J. C., Hsu, H. M., Hou, M. F., Orr, N., Schoemaker, M., Ashworth, A., Swerdlow, A., Trentham-Dietz, A., Newcomb, P. A., Titus, L., Egan, K. M., Chenevix-Trench, G., Antoniou, A. C., Humphreys, M. K., Morrison, J., Chang-Claude, J., Easton, D. F., and Dunning, A. M. Comparison of 6q25 Breast Cancer Hits from Asian and European Genome Wide Association Studies in the Breast Cancer Association Consortium (BCAC). PLoS One 7:e42380, 2012
  • Heinrich, S., Weigelt, I., Rapp, K., Becker, C., Rissmann, U., and Konig, H. H. [Fall and fracture prevention based on the National Expert Standard. Implementation and costs in a real world setting in nursing homes]. Z Gerontol Geriatr 45:128-137, 2012
  • Heinrich, S., Rapp, K., Stuhldreher, N., Rissmann, U., Becker, C., and Konig, H. H. Cost-effectiveness of a multifactorial fall prevention program in nursing homes. Osteoporos Int, 18-7-2012 Epub
  • Herrlinger, K. R., Diculescu, M., Fellermann, K., Hartmann, H., Howaldt, S., Nikolov, R., Petrov, A., Reindl, W., Otte, J. M., Stoynov, S., Strauch, U., Sturm, A., Voiosu, R., Ammendola, A., Dietrich, B., Hentsch, B., and Stange, E. F. Efficacy, safety and tolerability of vidofludimus in patients with inflammatory bowel disease: The ENTRANCE study. J Crohns Colitis , 15-10-2012 Epub
  • Hetzel, J., Eberhardt, R., Herth, F. J., Petermann, C., Reichle, G., Freitag, L., Dobbertin, I., Franke, K. J., Stanzel, F., Beyer, T., Moller, P., Fritz, P., Ott, G., Schnabel, P. A., Kastendieck, H., Lang, W., Morresi-Hauf, A. T., Szyrach, M. N., Muche, R., Shah, P. L., Babiak, A., and Hetzel, M. Cryobiopsy increases the diagnostic yield of endobronchial biopsy: a multicentre trial. Eur Respir.J 39:685-690, 2012
  • Hoffart, E., Ghebreghiorghis, L., Nussler, A. K., Thasler, W. E., Weiss, T. S., Schwab, M., and Burk, O. Effects of atorvastatin metabolites on induction of drug-metabolizing enzymes and membrane transporters through human pregnane X receptor. Br J Pharmacol 165:1595-1608, 2012
  • Hofmann, U., Heinkele, G., Angelberger, S., Schaeffeler, E., Lichtenberger, C., Jaeger, S., Reinisch, W., and Schwab, M. Simultaneous quantification of eleven thiopurine nucleotides by liquid chromatography-tandem mass spectrometry. Anal Chem 84:1294-1301, 7-2-2012
  • Hueber, W., Sands, B. E., Lewitzky, S., Vandemeulebroecke, M., Reinisch, W., Higgins, P. D., Wehkamp, J., Feagan, B. G., Yao, M. D., Karczewski, M., Karczewski, J., Pezous, N., Bek, S., Bruin, G., Mellgard, B., Berger, C., Londei, M., Bertolino, A. P., Tougas, G., and Travis, S. P. Secukinumab, a human anti-IL-17A monoclonal antibody, for moderate to severe Crohn's disease: unexpected results of a randomised, double-blind placebo-controlled trial. Gut 61:1693-1700, 2012
  • Husemann K, Falkenstern- Ge RF, Kohlhäufl M. Prolongierte paradoxe Reaktionen unter antituberkulöser Therapie nach Absetzen von Adalimumab -2 Fallbeispiele. Pneumologie 66(S01):P199, 2012
  • Iqbal, J., Shen, Y., Liu, Y., Fu, K., Jaffe, E. S., Liu, C., Liu, Z., Lachel, C. M., Deffenbacher, K., Greiner, T. C., Vose, J. M., Bhagavathi, S., Staudt, L. M., Rimsza, L., Rosenwald, A., Ott, G., Delabie, J., Campo, E., Braziel, R. M., Cook, J. R., Tubbs, R. R., Gascoyne, R. D., Armitage, J. O., Weisenburger, D. D., McKeithan, T. W., and Chan, W. C. Genome-wide miRNA profiling of mantle cell lymphoma reveals a distinct subgroup with poor prognosis. Blood 119:4939-4948, 24-5-2012
  • Johnson, N. A., Slack, G. W., Savage, K. J., Connors, J. M., Ben-Neriah, S., Rogic, S., Scott, D. W., Tan, K. L., Steidl, C., Sehn, L. H., Chan, W. C., Iqbal, J., Meyer, P. N., Lenz, G., Wright, G., Rimsza, L. M., Valentino, C., Brunhoeber, P., Grogan, T. M., Braziel, R. M., Cook, J. R., Tubbs, R. R., Weisenburger, D. D., Campo, E., Rosenwald, A., Ott, G., Delabie, J., Holcroft, C., Jaffe, E. S., Staudt, L. M., and Gascoyne, R. D. Concurrent expression of MYC and BCL2 in diffuse large B-cell lymphoma treated with rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone. J Clin Oncol 30:3452-3459, 1-10-2012
  • Justenhoven, C., Obazee, O., Winter, S., Couch, F. J., Olson, J. E., Hall, P., Hannelius, U., Li, J., Humphreys, K., Severi, G., Giles, G., Southey, M., Baglietto, L., Fasching, P. A., Beckmann, M. W., Ekici, A. B., Hamann, U., Baisch, C., Harth, V., Rabstein, S., Lotz, A., Pesch, B., Bruning, T., Ko, Y. D., and Brauch, H. The postmenopausal hormone replacement therapy-related breast cancer risk is decreased in women carrying the CYP2C19*17 variant. Breast Cancer Res Treat. 131:347-350, 2012
  • Karagianni, A., Muhlfeld, C., Bode-Erdmann, S., Vohringer, M., and Sechtem, U. Primary cardiac lymphoma causing coronary vasospasm. Eur Heart J Cardiovasc Imaging 13:775, 2012
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  • Kimmel M, Braun N, and Alscher MD. Chronische Niereninsuffizienz. Ars medici 20:1096-1098, 2012
  • Kimmel M, Braun N, and Alscher MD. Chronische Niereninsuffizienz. Der Allgemeinarzt 7:18-20, 2012
  • Klotz, U. Paracetamol (acetaminophen) - a popular and widely used nonopioid analgesic. Arzneimittelforschung. 62:355-359, 2012
  • Klotz, U. The pharmacological profile and clinical use of mesalazine (5-aminosalicylic acid). Arzneimittelforschung. 62:53-58, 2012
  • Kohlhaufl M. Pneumologie. In: Braun V; Jobst D; Martin S; Wetzel-Richter D (Hrsg) Hand Allgemeinmedizin 2012.ISBN 987-3-86302-045-3 med publico GmbH, 2012
  • Kroegel, C., Haidl, P., Kohlhaufl M, and Voshaar, T. Bronchiolitis part 2 - Diagnostischer Zugang und Therapie. Pneumologie 66:78-88, 2012
  • Kroegel, C., Haidl, P., Kohlhaufl, M., and Voshaar, T. [Bronchiolitis. Part 1--anatomic features, classification, clinical presentation and imaging]. Pneumologie 66:28-38, 2012
  • Lang H. Depression, Klinik, Ursachen, Therapie. Königshausen & Neumann Würzburg:135-144, 2012
  • Lang T, Arlanov R, and Schwab M. Untersuchungen zu ABCC2-Varianten in einem Tet-Off Expressionssystem. BIOspektrum, Wissenschaft - Special: Genomics 18:280-283, 2012
  • Latus J, Alscher MD, Schaeffeler E, Braun N, and Schwab M. Arzneimittelassoziierte Störungen des Säure-Basen-Haushalts. Der Nephrologe 7:490-498, 2012
  • Liepelt-Scarfone, I., Jamour, M., and Maetzler, W. Co-occurrence of parkinsonism and dementia in clinical practice: relevant differential diagnoses. Z Gerontol Geriatr 45:23-33, 2012
  • Nies, A. T., Damme, K., Schaeffeler, E., and Schwab, M. Multidrug and toxin extrusion (MATE) proteins as transporters of antimicrobial drugs. Expert Opin Drug Metab Toxicol 8:1565-1577, 13-9-2012
  • Nies, AT., Resch, C., and Namisaki, T. Transporting systems. In: Anzenbacher P, Zanger UM (eds.). Metabolism of Drugs and other Xenobiotics, Wiley-VCH Verlag GmbH & Co.KGaA:199-222, 2012
  • Ong, P., Greulich, S., Schumm, J., Backes, M., Kaufmann, M., Bode-Erdmann, S., Ott, G., Hebart, H., and Mahrholdt, H. Favorable course of pericardial angiosarcoma under Paclitaxel followed by pazopanib treatment documented by cardiovascular magnetic resonance imaging. Circulation 126:e279-e281, 30-10-2012
  • Orhan, G., Wuttke, T. V., Nies, A. T., Schwab, M., and Lerche, H. Retigabine/Ezogabine, a KCNQ/K(V)7 channel opener: pharmacological and clinical data. Expert Opin Pharmacother 13:1807-1816, 2012
  • Rieder, F., Karrasch, T., Ben-Horin, S., Schirbel, A., Ehehalt, R., Wehkamp, J., de, Haar C., Velin, D., Latella, G., Scaldaferri, F., Rogler, G., Higgins, P., and Sans, M. Results of the 2nd scientific workshop of the ECCO (III): basic mechanisms of intestinal healing. J Crohns Colitis 6:373-385, 2012
  • Schroeder, B. O., Stange, E. F., and Wehkamp, J. [Human beta-Defensin 1: From Defence to Offence]. Z Gastroenterol 50:1171-1175, 2012
  • Schwab M, Schaeffeler E, and Brauch H. Anticancer Drugs (Chapter 13). In: Anzenbacher P, Zanger UM (eds.). Metabolism of Drugs and other Xenobiotics.Wiley-VCH Verlag GmbH & Co.KGaA chapter 13:365-378, 2012
  • Shi, S. and Klotz, U. Drug interactions with herbal medicines. Clin Pharmacokinet 51:77-104, 1-2-2012
  • Teml A, Karner S, Schaeffeler E, and Schwab M. Pharmacogenomics of Inflammatory Bowel Diseases (Chapter 11). In: Maitland-van der Zee AH, Daly AK (ed). Pharmacogenetics and Individualized Therapy.John Wiley & Sons Inc.:323-351, 2012
  • Zanger UM, Thomas M, Kerb R, Hofmann U, Kandel B, Klein M, and Schwab M. Biotransformation von Fremdstoffen in der Leber: Systembiologische Ansätze zur Vorhersage von Arzneimittelwirkungen. Systembiologie.de 05:65-68, 2012
  • Anzenbacher P and Zanger UM. Metabolism of Drugs and other Drugs and other Xenobiotics. Wiley-VCH, 2012
  • Auffray, C., Caulfield, T., Khoury, M. J., Lupski, J. R., Schwab, M., and Veenstra, T. Looking back at genomic medicine in 2011. Genome Med 4:9, 2012
  • Benzinger P. Moving outdoor in older adults: assessment based on accelerometer data. Mobex, 2012
  • Falkenstern-Ge RF, Ott G, Friedel G, Markmann HU, Kohlhäufl M, and Kalla J. Bronchial sialadenoma papilliferum: a very rare cause of hemoptysis. Journal of Cancer Science and Therapy 3:20-21, 2012
  • Ott, M. M., Horn, H., Kaufmann, M., and Ott, G. The Hans classificator does not predict outcome in diffuse large B cell lymphoma in a large multicenter retrospective analysis of R-CHOP treated patients. Leuk Res 36:544-545, 2012
  • Pfeiffer K, Beische D, and Hautzinger M. Coaching und Problemlösetraining für pflegende Angehörige von Schlaganfallpatienten. Hilfen für die ambulante häusliche Pflege, 2012
  • Pfeiffer K, Kuepper M, Stranzinger K, Klein D, Becker C, and Hautzinger M. Identifying and Addressing Fear of Falling in Hip Fracture Patients ? Preliminary Results of a Multifactorial Intervention. 18th World Congress on Active Ageing, 2012 invited speaker
  • Rapp, K., Koenig HH, and Becker C. Primärprävention von sturzbedingten Hüftfrakturen bei Bewohnern von Pflegeheimen in Bayern. Public Health Forum 20 74, 2012
  • Riedmaier S and Zanger UM. Cardiovascular Drugs. In: Metabolism of Drugs and other Xenobiotics (eds, P. Anzenbacher and U.M. Zanger chapt. 12). Wiley-VCH 2012:331-363, 2012
  • Schwab, M. and Moerike, K. Antiarrhythmic drug treatment after cardioversion of atrial fibrillation. Lancet 380:1467, 27-10-2012
  • Teichgraber, U., Atreya, I., Atreya, R., Schwab, M., and Neurath, M. F. Infliximab treatment induces levels of the active azathioprine metabolite TGTP in Crohn's disease. Inflamm.Bowel Dis 2012, Epub 
  • Weiss H. Perversion und Spaltung. In: Reiser-Mumme U., von Tippelskirch-Eissing, Teising M., Walker Ch. (Hg.), Spaltung: Entwicklung und Stillstand. Tagungsband. Deutsche Psychoanalytische Vereinigung:324-331, 2012
  • Weiss H. Lernen durch Erfahrung oder Ausbildung nach dem Modell von Totem und Tabu? Versionen der Ödipussituation in der psychoanalytischen Institution. In: Teising M., Walker CH. Hg., Generativität und Generationenkonflikte. Tagungsband. Deutsche Psychoanalytische Vereinigung:389-399, 2012
  • Zanger UM. Introduction to Drug Metabolism. In: Metabolism of Drugs and other Xenobiotics (eds P. Anzenbacher and U.M. Zanger, chapt. 0). Wiley-VCH 2012:287-3001, 2012
  • Zanger UM. Cytochrome P450 Polymorphisms. In: Encyclopedia of Drug Metabolism and Interactions (Editor A.V. Lyubimov)(chapt. 9). John Wiley & Sons, Inc.Hoboken, New Jersey 1, 2012
  • Zanger UM, Klein K, and Rieger J. The Importance of Pharmacogenomics. In: Metabolism of Drugs and other Xenobiotics (eds P. Anzenbacher and U.M. Zanger, chapt. 9). Wiley-VCH 2012:259-284, 2012
Habilitations
  • Yilmaz, Ali
    Kardiale Beteiligung bei hereditären neuromuskulären Erkrankungen: neue Erkenntnisse durch Anwendung der kardialen Magnetresonanztomographie, Eberhard-Karls Universität Tübingen.
  • Franke, Ulrich
    Umhabilitation und Ernennung zum außerplanmäßigen Professor, Eberhard-Karls Universität Tübingen.


PHD/MD Theses


  • Ahad, Samir
    Vergleichende Analyse der Ergebnisse des Aortenklappenersatzes bei Hochrisikopatienten, Medizinische Fakultät, Eberhard Karls Universität Tübingen.
  • Akhavan, Fariba
    Beurteilung der Rehabilitationsfortschritte nach Gelenkersatz bei älteren Menschen. Medizinische Fakultät, Universität Ulm .
  • Cheng, Fei
    Pathogenetische Bedeutung der Glutathionperoxidase-1 (Gpx-1) in der arteriellen Gefäßwand, Fachbereich Biologie, Johannes Gutenberg-Universität Mainz.
  • Nicolai, Simone
    Bedeutung und Messung körperlicher Aktivität bei Patienten der geriatrischen Rehabilitation. Institut für Sport- und Bewegungswissenschaft, Universität Stuttgart .
  • Ostaff, Maureen J.
    Disease underlying genetics in ileal Crohn’s Disease: Disturbed antimicrobial defense and impaired Wnt signaling at the epithelial barrier. Eberhard-Karls Universität Tübingen
  • Rieger, Jessica Karin
    Neue Methoden und Forschungs-Ansätze zur Bedeutung von microRNAs in der Leber und in Hepatozyten. Mathematisch-Naturwissenschaftliche Fakultät der Eberhard-Karls Universität Tübingen.
  • Seo, E-J
    Construction of recombinant E. coli Nissle 1917 (EcN) strains expressing/secreting defensins; University of Wuerzburg.
  • Troge, A
    Studies on the flagellar system of Escherichia coli Nissle 1917 (EcN) with regard to its function as a probiotic; University of Wuerzburg.


Diploma / Master Theses


  • Bausinger, Julia
    Analyse chromosomaler Deletionen zur Risikostratifizierung follikulärer Lymphome mittels Fluoreszenz in situ Hybridisierung, Studiengang Biologie, Universität Hohenheim.
  • Müller, Janina
    Interaktion zwischen Promotor und distalem Enhancer während der MDR1-Induktion durch Kernrezeptoren. Fakultät für Energie-, Verfahrens- und Biotechnik der Universität Stuttgart.
  • Schaaf, Lea
    Der Einfluss der c-Abl Hemmung auf die Prozessierung von DNA-Schäden nach Alkylanz Behandlung. Fakultät für Naturwissenschaften, Universität Stuttgart-Hohenheim.
  • Traub, Stefanie
    Die Untersuchung der Expression und Lokalisation von Kernrezeptoren im exkretorischen System (Niere/Blase) des Menschen. Fakultät Naturwissenschaften, Universität Hohenheim .