Curriculum Vitae Julia Beisner, PhD
Affiliation
Senior Research Scientist at the Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart and University of Tübingen
Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology
Auerbachstr. 112
D-70376 Stuttgart
phone: ++49-711-8101 5758
fax: ++49-711-859295
email: julia.beisner@ikp-stuttgart.de
Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology
Auerbachstr. 112
D-70376 Stuttgart
phone: ++49-711-8101 5758
fax: ++49-711-859295
email: julia.beisner@ikp-stuttgart.de
Dr. rer. nat. Julia Beisner
phone: ++49-711-8101 5758
Education and Professional Career
| 1994-2000 | Studies in biology, Johannes-Gutenberg University, Mainz |
| 2001 | Diploma thesis, Johannes-Gutenberg University, Mainz |
| 2001-2005 | PhD thesis at the Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology |
| 2005 | Dr. rer. nat (PhD) in Biology, University of Stuttgart |
| 2005-2008 | Research Scientist at the Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart |
| 2008-present | Senior Research Scientist in gastrointestinal research ‘Antimicrobial host response in the gastrointestinal tract’, Dr. Jan Wehkamp, Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology |
Professional Memberships
Deutsche Gesellschaft für Verdauungs- und Stoffwechselstörungen (DGVS)
Selected References
- Schroeder BO, Wu Z, Nuding S, Groscurth S, Marcinowski M, Beisner J, Buchner J, Schaller M, Stange EF, Wehkamp J: Reduction of disulphide bonds unmasks potent antimicrobial activity of human β-defensin 1. Nature 2011; 469:419-23.
- Beisner J, Stange EF, Wehkamp J: Innate antimicrobial immunity in inflammatory bowel diseases. Expert Rev Clin Immunol 2010; 6:809-18.
- Peyrin-Biroulet L, Beisner J, Wang G, Nuding S, Oommen ST, Kelly D, Parmentier-Decrucq E, Dessein R, Merour E, Chavatte P, Grandjean T, Bressenot A, Desreumaux P, Colombel JF, Desvergne B, Stange EF, Wehkamp J, Chamaillard M: Peroxisome proliferator-activated receptor gamma activation is required for maintenance of innate antimicrobial immunity in the colon. Proc Natl Acad Sci U S A 2010; 107:8772-7.
- Perminow G, Beisner J, Koslowski M, Lyckander LG, Stange E, Vatn MH, Wehkamp J: Defective Paneth Cell-Mediated Host Defense in Pediatric Ileal Crohn's Disease. Am J Gastroenterol 2010; 105:452-9.
- Koslowski MJ, Kübler I, Chamaillard M, Schaeffeler E, Reinisch W, Wang G, Beisner J, Teml A, Peyrin-Biroulet L, Winter S, Herrlinger KR, Rutgeerts P, Vermeire S, Cooney R, Fellermann K, Jewell D, Bevins CL, Schwab M, Stange EF and Wehkamp J: Genetic variants of Wnt transcription factor Tcf-4 (Tcf7L2) putative promoter region are associated with small intestinal Crohn´s disease. Public library of Science (PLOS) one 2009; 4:e4496.
- Kübler I, Koslowski MJ, Gersemann M, Fellermann K, Beisner J, Becker S, Rothfuss K, Herrlinger KR, Stange EF, Wehkamp J: Influence of standard treatment on ileal and colonic antimicrobial defensin expression in active Crohn's disease. Aliment Pharmacol Ther 2009; 30:621-33.
- Möndel M, Schroeder BO, Zimmermann K, Huber H, Nuding S, Beisner J, Fellermann K, Stange EF, Wehkamp J: Probiotic E. coli treatment mediates antimicrobial human ß-defensin synthesis and fecal excretion in humans. Mucosal Immunology 2009; 2:166-72.
- Beisner J, Dong M, Taetz S, Nafee N, Griese EU, Schaefer U, Lehr CM, Klotz U, Mürdter TE: Nanoparticle mediated delivery of 2'-O-methyl-RNA leads to efficient telomerase inhibition and telomere shortening in human lung cancer cells. Lung Cancer 2010; 68:346-54.
- Beisner J, Buck MB, Fritz P, Dippon J, Schwab M, Brauch H, Zugmaier G, Pfizenmaier K, Knabbe C: A novel functional polymorphism in the transforming growth factor-beta2 gene promoter and tumor progression in breast cancer. Cancer Res 2006; 66:7554-61.